Prdx5 - peroxiredoxin 5 Gene

Also Known as PLP; AOPP; PrxV; Pmp20; Prdx6; AOEB166

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54683

Summary

This gene encodes a member of the peroxiredoxin family of antioxidant Enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites may result in use of alternate in-frame translation start codons that generate alternate isoforms that are targeted to the mitochondrion or peroxisome/cytoplasm. [provided by RefSeq, Nov 2017]

Prdx5 Products (2)

mRNA Protein Name
NM_001358444.1 NP_001345373.1 peroxiredoxin-5, mitochondrial isoform 2 precursor
NM_012021.3 NP_036151.1 peroxiredoxin-5, mitochondrial isoform 1 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
29128334 MGI
enables thioredoxin-dependent peroxiredoxin activity IDA
IDA: Inferred from direct assay
10679306 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peroxiredoxin-5, mitochondrial

  • antioxidant enzyme B166

  • liver tissue 2D-page spot 2D-0014IV

  • peroxiredoxin 6

  • peroxiredoxin V

  • peroxisomal antioxidant enzyme

  • peroxisomal membrane protein 20

  • thioredoxin peroxidase PMP20

  • thioredoxin reductase

  • thioredoxin-dependent peroxiredoxin 5

Recombinant Prdx5 Proteins

Cat. No. Product Name Accession Purity
HY-P73375 PRDX5/Peroxiredoxin-5 Protein, Mouse (His) P99029-1 (M49-L210) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N3225 Myricanol 98.93% Unkown
HY-RS11078 PRDX5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17470 Prdx6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17919 Prdx5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24388 Prdx5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prdx5 NCBI NCBI:25824