IL26 - interleukin 26 Gene

Also Known as AK155; IL-26

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55801

About IL26

Cytogenetic location: 12q15 Genomic coordinates (GRCh38): 12:68,201,349-68,225,810 (from NCBI)

This gene has 1 transcript (splice variant), 70 orthologues and 4 paralogues. Low expression observed in reference dataset.

Summary

This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after Infection by herpesvirus samimiri. [provided by RefSeq, Jul 2008]

IL26 Products (1)

mRNA Protein Name
NM_018402.2 NP_060872.1 interleukin-26 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cytokine activity IDA
IDA: Inferred from direct assay
18483078 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of epithelial cell proliferation IDA
IDA: Inferred from direct assay
18483078 GOA
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: Inferred from direct assay
18483078 GOA
involved in positive regulation of cytokine production IDA
IDA: Inferred from direct assay
18483078 GOA
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: Inferred from direct assay
18483078 GOA
involved in positive regulation of receptor signaling pathway via JAK-STAT IDA
IDA: Inferred from direct assay
18483078 GOA
involved in positive regulation of stress-activated MAPK cascade IDA
IDA: Inferred from direct assay
18483078 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18483078 GOA
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
18483078 GOA
located in extracellular space IDA
IDA: Inferred from direct assay
18483078 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IL26 Protein Structure

IL10

IL10: Interleukin 10 (8 - 164)

  • 0
  • 100
  • 171 a.a.
Protein Preferred Names Protein Names

interleukin-26

Recombinant IL26 Proteins

Cat. No. Product Name Accession Purity
HY-P700117AF Animal-Free IL-26/AK155 Protein, Human (His) Q9NPH9 (K22-Q171) ≥ 95%, as determined by reducing SDS-PAGE.

IL26 Antibodies

Cat. No. Product Name Application Reactivity
HY-P83270 IL-26 Antibody (YA3015) WB, IHC-P, ICC/IF, IP Human
HY-P83270A IL-26 Antibody (YA3015)(PBS only) WB, IHC-P, IP Human

Related Diseases

Diseases Alias
Crohn'S Disease

  • Crohn Disease

  • Pediatric Crohn'S Disease

  • Regional Enteritis

  • Crohn'S Disease Of Large Bowel

  • Granulomatous Colitis

  • Enteritis, Granulomatous

  • Enteritis

  • Crohn'S Disease Of Colon

  • Colitis, Granulomatous

  • Crohn'S Enteritis

  • Enteritis, Regional

  • Ileitis

  • Adenoviral Enteritis

  • Acute Gastroenteropathy Due To Norwalk Agent

  • Viral Gastroenteritis Due To Norwalk Agent

  • Winter Vomiting

  • Epidemic Winter Vomiting Disease

  • Small Round Structured Virus Enteritis

  • Epidemic Vomiting Syndrome

  • Epidemic Vomiting

  • Epidemic Nausea

  • Epidemic Viral Gastroenteritis Due To Norwalk Virus

  • Noroviral Enteritis

  • Crohn Disease Nos

  • Crohns

  • Cd - [Crohn'S Disease]

  • Regional Enteritis Of Bowel

  • Crohn'S Regional Enteritis

  • Cobble-Stone Appearance Of Intestine

  • Intestinal Ulcer And Erosion Due To Crohn Disease

  • Granulomatous Enteritis
Hidradenitis Suppurativa

  • Acne Inversa

  • Suppurative Hidradenitis

  • Acne Inversa, Familial

  • Apocrinitis

  • Hidradenitides, Suppurative

  • Hidradenitis, Suppurative

  • Suppurative Hidradenitides

  • Inverse Acne
Hidradenitis

  • Hydradenitis
Inflammatory Bowel Disease

  • Inflammatory Bowel Diseases

  • Bowel Disease, Inflammatory
Psoriasis 12

  • PSORS12

  • Psoriasis Susceptibility 12

  • Psoriasis 12, Susceptibility To
Rheumatoid Arthritis

  • RA

  • Arthritis, Rheumatoid

  • Rheumatoid Arthritis, Susceptibility To

  • Arthritis Or Polyarthritis, Rheumatic

  • Atrophic Arthritis

  • Rheumatism Arthritis

  • Rheumatoid Polyarthritis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06745 IL26 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174614 Human IL26 mRNA / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992245 Anti-IL-26 Antibody / Unkown