PRM1 - protamine 1 Gene

Also Known as P1; CT94.1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 5619

About PRM1

Cytogenetic location: 16p13.13 Genomic coordinates (GRCh38): 16:11,280,841-11,281,330 (from NCBI)

This gene has 1 transcript (splice variant) and 17 orthologues. Restricted expression toward testis (RPKM 2212.7).

Summary

Predicted to enable DNA binding activity. Predicted to be involved in DNA packaging. Predicted to act upstream of or within nucleus organization and spermatid development. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PRM1 Products (1)

mRNA Protein Name
NM_002761.3 NP_002752.1 sperm protamine P1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PRM1 Protein Structure

Protamine_P1

Protamine_P1: Protamine P1 (2 - 50)

  • 0
  • 51 a.a.
Protein Preferred Names Protein Names

sperm protamine P1

  • cancer/testis antigen family 94, member 1

PRM1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PRM1 P04553 CLK2 Homo sapiens P49760
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Male Infertility

  • Infertility, Male

  • Infertility Male

  • Male Sterility

  • Absolute Infertility
Infertility
Varicocele

  • Scrotal Varices

  • Varicoceles

  • Varicocele Of Scrotum

  • Scrotal Varicocele
Spermatogenic Failure

  • Azoospermia

  • Spgf

  • Spermatogenic Failure, Susceptibility To

  • Absent Sperm

  • Aspermatogenesis

  • Infertility Due To Azoospermia

  • Hypospermatogenesis

  • Azoospermatism
Nickel Allergic Contact Dermatitis

  • Allergic Contact Dermatitis To Ni
Pelvic Varices

  • Varix Of Pelvis

  • Pelvic Varicose Vein
Oligoasthenoteratozoospermia

  • Oat

  • Oligoasthenoteratospermia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11164 PRM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11480 PXDNL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus PRM1 MGD MGI:97765
Rattus norvegicus PRM1 RGD RGD:1583873
Others PRM1 NCBI