Abcb10 - ATP-binding cassette, sub-family B (MDR/TAP), member 10 Gene

Also Known as Abc-me; Abcb12

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56199

Summary

This gene encodes a member of the ATP-binding cassette superfamily of transporters. ATP-binding cassette proteins transport various molecules across extra- and intra-cellular membranes. The encoded protein is localized to the mitochondrial inner membrane where it interacts with and stabilizes mitoferrin-1, and is important for heme biosynthesis. Additional evidence suggests the encoded protein is involved in oxidative stress protection and erythropoisesis. [provided by RefSeq, May 2013]

Abcb10 Products (1)

mRNA Protein Name
NM_019552.2 NP_062425.1 ATP-binding cassette sub-family B member 10, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP binding IDA
IDA: Inferred from direct assay
26053025 MGI
enables ATP hydrolysis activity IDA
IDA: Inferred from direct assay
33253225 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
15215243 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
19805291 MGI
Biological Process GO Annotation Evidence References Source
involved in heme biosynthetic process IMP
IMP: Inferred from mutant phenotype
24421385 MGI
involved in positive regulation of erythrocyte differentiation IMP
IMP: Inferred from mutant phenotype
22240895 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
10835348 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
15215243 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP-binding cassette sub-family B member 10, mitochondrial

  • ABC-mitochondrial erythroid protein

  • ATP-binding cassette transporter 10

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-D1063 IR-780 99.82% Unkown
HY-RS00049 ABCB10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21085 Abcb10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27603 Abcb10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abcb10 NCBI NCBI:23456