2. Gene
  3. FEM1C - fem-1 homolog C Gene

FEM1C - fem-1 homolog C Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as FEM1A; EUROIMAGE686608; EUROIMAGE783647

Gene ID: 56929 | Gene type: protein coding

About FEM1C

Cytogenetic location: 5q22.3 Genomic coordinates (GRCh38): 5:115,520,908-115,544,775 (from NCBI)

This gene has 1 transcript (splice variant), 209 orthologues and 4 paralogues. Ubiquitous expression in bone marrow (RPKM 24.9), testis (RPKM 9.4) and 25 other tissues.

Summary

Enables ubiquitin ligase-substrate adaptor activity. Involved in ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Located in cytosol and nucleoplasm. Part of Cul2-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

FEM1C Products(1)

mRNA Protein Name
NM_020177.3 NP_064562.1 protein fem-1 homolog C

FEM1C Protein Structure

Ank_4

Ank_4: Ankyrin repeats (many copies) (5 - 61)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (88 - 178)

Ank

Ank: Ankyrin repeat (182 - 206)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (481 - 557)

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  • 617 a.a.
Protein Preferred Names Protein Names

protein fem-1 homolog C

FEM1-gamma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04860 FEM1C Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus FEM1C RGD RGD:1309322
Macaca mulatta FEM1C VGNC VGNC:110466
Bos taurus FEM1C VGNC VGNC:28946
Mus musculus FEM1C MGD MGI:2444737
Felis catus FEM1C VGNC VGNC:62225
Canis familiaris FEM1C VGNC VGNC:51719