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No matches for "

57707

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8

Inhibitors & Agonists

1

Isotope-Labeled Compounds

4

Antibodies

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145588
    Povorcitinib

    INCB54707

    		 JAK Inflammation/Immunology
    Povorcitinib (INCB54707) is a potent and selective JAK1 inhibitor that effectively reduces abscesses and inflammatory nodules. Povorcitinib is used to study cutaneous lupus erythematosus (CLE) and lichen planus (LP) .
    Povorcitinib
  • HY-161696
    AN5777

    		Apoptosis Cancer
    AN5777 is a GSPT1 degrader. AN5777 significantly reduces GSPT1 through the ubiquitin-proteasome system. AN5777 induces G1 block and Apoptosis. AN5777 has antitumor activity .
    AN5777
  • HY-145588A
    Povorcitinib phosphate

    INCB54707 phosphate

    		 JAK Inflammation/Immunology
    Povorcitinib (INCB54707) phosphate is a potent and selective JAK1 inhibitor that effectively reduces abscesses and inflammatory nodules. Povorcitinib phosphate can be used to study cutaneous lupus erythematosus (CLE) and lichen planus (LP) (information extracted from patent WO2021076124A1) .
    Povorcitinib phosphate
  • HY-R01790
    hsa-miR-5707 mimic

    		MicroRNA Cancer
    hsa-miR-5707 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-5707 mimic
    hsa-miR-5707 mimic
  • HY-145588S
    Povorcitinib-d6

    INCB54707-d6

    		 Isotope-Labeled Compounds JAK Inflammation/Immunology
    Povorcitinib-d6 (INCB54707-d6) is the deuterium labeled Povorcitinib (HY-145588). Povorcitinib (INCB54707) is a potent and selective JAK1 inhibitor that effectively reduces abscesses and inflammatory nodules. Povorcitinib is used to study cutaneous lupus erythematosus (CLE) and lichen planus (LP) .
    Povorcitinib-d6
  • HY-RI01790
    hsa-miR-5707 inhibitor

    		MicroRNA Cancer
    hsa-miR-5707 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-5707 inhibitor
    hsa-miR-5707 inhibitor
  • HY-RI01790A
    hsa-miR-5707 antagomir

    		MicroRNA Cancer
    hsa-miR-5707 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-5707 antagomir
    hsa-miR-5707 antagomir
  • HY-R01790A
    hsa-miR-5707 agomir

    		MicroRNA Cancer
    hsa-miR-5707 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-5707 agomir
    hsa-miR-5707 agomir

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