MEAK7 - MTOR associated protein MEAK7 Gene

Also Known as EAK7; TLDC1; mEAK-7; KIAA1609

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57707

Summary

Involved in several processes, including TOR signaling; positive regulation of protein localization to lysosome; and response to Insulin. Located in cytosol and lysosomal membrane. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in placenta (RPKM 6.1), esophagus (RPKM 5.1) and 23 other tissues.

MEAK7 Products (1)

mRNA Protein Name
NM_020947.4 NP_065998.3 MTOR-associated protein MEAK7
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Biological Process GO Annotation Evidence References Source
involved in TOR signaling IMP
IMP: Inferred from mutant phenotype
29750193 GOA
involved in positive regulation of protein localization to lysosome IDA
IDA: Inferred from direct assay
29750193 GOA
involved in regulation of cell migration IDA
IDA: Inferred from direct assay
29750193 GOA
involved in regulation of cell population proliferation IDA
IDA: Inferred from direct assay
29750193 GOA
involved in response to amino acid IDA
IDA: Inferred from direct assay
29750193 GOA
involved in response to insulin IDA
IDA: Inferred from direct assay
29750193 GOA
involved in response to nutrient levels IDA
IDA: Inferred from direct assay
29750193 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
24223779 GOA
located in lysosomal membrane IDA
IDA: Inferred from direct assay
29750193 GOA
located in membrane IDA
IDA: Inferred from direct assay
24223779 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MEAK7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
MEAK7 Q6P9B6 TRIP13 Homo sapiens Q15645 31515488
Cross: Cross-species interaction Intra: Intraspecies interaction