2. Gene
  3. CYP4F11 - cytochrome P450 family 4 subfamily F member 11 Gene

CYP4F11 - cytochrome P450 family 4 subfamily F member 11 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CYPIVF11

Gene ID: 57834 | Gene type: protein coding

About CYP4F11

Cytogenetic location: 19p13.12 Genomic coordinates (GRCh38): 19:15,912,377-15,934,867 (from NCBI)

This gene has 5 transcripts (splice variants), 381 orthologues and 12 paralogues. Biased expression in liver (RPKM 19.6), gall bladder (RPKM 11.3) and 11 other tissues.

Summary

This gene, CYP4F11, encodes a member of the Cytochrome P450 superfamily of enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of Cholesterol, Steroids and other lipids. This gene is part of a cluster of Cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

CYP4F11 Products(2)

mRNA Protein Name
NM_001128932.2 NP_001122404.1 cytochrome P450 4F11 precursor
NM_021187.4 NP_067010.3 cytochrome P450 4F11 precursor

CYP4F11 Protein Structure

p450

p450: Cytochrome P450 (52 - 505)

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  • 524 a.a.
Protein Preferred Names Protein Names

cytochrome P450 4F11

3-hydroxy fatty acids omega-hydroxylase CYP4F11

Related Diseases

Diseases Alias
Bietti Crystalline Corneoretinal Dystrophy

BCD

Bietti Crystalline Dystrophy

Bietti Tapetoretinal Degeneration With Marginal Corneal Dystrophy

Bietti Crystalline Retinopathy

Bietti'S Crystalline Dystrophy

Crystalline Retinopathy

Dystrophy, Corneoretinal, Crystalline, Bietti
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03478 CYP4F11 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CYP4F11 RGD RGD:1559596
Macaca mulatta CYP4F11 VGNC VGNC:103612