PGAP6 - post-GPI attachment to proteins 6 Gene

Also Known as M83; TMEM6; TMEM8; TMEM8A; GPI-PLA2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 58986

Summary

Predicted to enable A2-type glycerophospholipase activity. Predicted to be involved in lipid metabolic process. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in testis (RPKM 24.1), placenta (RPKM 22.5) and 25 other tissues.

PGAP6 Products (1)

mRNA Protein Name
NM_021259.3 NP_067082.2 post-GPI attachment to proteins factor 6 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PGAP6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PGAP6 Q9HCN3 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
Intra
PGAP6 Q9HCN3 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
Intra
PGAP6 Q9HCN3 REL Homo sapiens Q04864-2
Y2H Prey Pooling
32296183
Intra
PGAP6 Q9HCN3 REL Homo sapiens Q04864-2
Y2H Array
32296183
Intra
PGAP6 Q9HCN3 KRTAP12-3 Homo sapiens P60328
Y2H Array
32296183
Intra
PGAP6 Q9HCN3 KRTAP12-3 Homo sapiens P60328
Y2H Prey Pooling
32296183
Intra
PGAP6 Q9HCN3 KRTAP1-1 Homo sapiens Q07627
Y2H Prey Pooling
32296183
Intra
PGAP6 Q9HCN3 KRTAP1-1 Homo sapiens Q07627
Y2H Array
32296183
Intra
PGAP6 Q9HCN3 NOTCH2NLC Homo sapiens P0DPK4
Y2H Prey Pooling
32296183
Intra
PGAP6 Q9HCN3 NOTCH2NLC Homo sapiens P0DPK4
Y2H Array
32296183
Intra
PGAP6 Q9HCN3 KRTAP6-3 Homo sapiens Q3LI67
Validated Y2H
32296183
Intra
PGAP6 Q9HCN3 KRTAP6-3 Homo sapiens Q3LI67
Y2H Array
32296183
Intra
PGAP6 Q9HCN3 KRTAP6-3 Homo sapiens Q3LI67
Y2H Prey Pooling
32296183
Intra
PGAP6 Q9HCN3 CYSRT1 Homo sapiens A8MQ03
Validated Y2H
32296183
Intra
PGAP6 Q9HCN3 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra
PGAP6 Q9HCN3 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
PGAP6 Q9HCN3 KRTAP5-9 Homo sapiens P26371
Y2H Prey Pooling
32296183
Intra
PGAP6 Q9HCN3 KRTAP5-9 Homo sapiens P26371
Y2H Array
32296183
Intra
PGAP6 Q9HCN3 HNRNPK Homo sapiens P61978-2
Y2H Array
32296183
Intra
PGAP6 Q9HCN3 HNRNPK Homo sapiens P61978-2
Y2H Prey Pooling
32296183
Intra
PGAP6 Q9HCN3 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
PGAP6 Q9HCN3 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10377 PGAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10378 PGAP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21019 Pgap1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27536 Pgap1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown