PAK2 - p21 (RAC1) activated kinase 2 Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 612814

About PAK2

Primary_assembly 33: 30,018,587-30,235,797 forward strand.ROS_Cfam_1.0:CM025132.1

This gene has 3 transcripts (splice variants), 295 orthologues and 36 paralogues.

PAK2 Products (2)

mRNA Protein Name
XM_038445288.1 XP_038301216.1 serine/threonine-protein kinase PAK 2 isoform X1
XM_038445289.1 XP_038301217.1 serine/threonine-protein kinase PAK 2 isoform X2

PAK2 Protein Structure

PBD

PBD: pfam00786 (72 - 129)

STKc_PAK2

STKc_PAK2: cd06655 (228 - 523)

  • 0
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  • 400
  • 500
  • 524 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase PAK 2

  • p21 (CDKN1A)-activated kinase 2

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-13007 PF-3758309 Inhibitor 99.79% Phase 1
HY-13007A PF-3758309 hydrochloride Inhibitor / Phase 1
HY-13007B PF-3758309 dihydrochloride Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15542A FRAX597 Inhibitor 99.36% Unkown
HY-15542B FRAX486 Inhibitor 98.10% Unkown
HY-19635 G-5555 Inhibitor 99.88% Unkown
HY-19538 FRAX1036 Inhibitor 98.88% Unkown
HY-120940 AZ13705339 Inhibitor 98.57% Unkown
HY-19635A G-5555 hydrochloride Inhibitor 98.26% Unkown
HY-171034 PQA-18 Inhibitor 99.62% Unkown
HY-131043 NVS-PAK1-C Inhibitor 99.2% Unkown
HY-120940A AZ13705339 hemihydrate Inhibitor 99.77% Unkown
HY-182357 PAK1-IN-3 Inhibitor / Unkown
HY-116917 G-9791 Inhibitor / Unkown
HY-146786 ZMF-10 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PAK2 NCBI NCBI:5062