2. Gene
  3. CENPK - centromere protein K Gene

CENPK - centromere protein K Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as P33; Solt; CENP-K; FKSG14; AF5alpha

Gene ID: 64105 | Gene type: protein coding

About CENPK

Cytogenetic location: 5q12.3 Genomic coordinates (GRCh38): 5:65,495,624-65,563,168 (from NCBI)

This gene has 17 transcripts (splice variants) and 197 orthologues. Broad expression in testis (RPKM 1.8), bone marrow (RPKM 1.7) and 19 other tissues.

Summary

CENPK is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM, Mar 2008]

CENPK Products(5)

mRNA Protein Name
NM_001267038.2 NP_001253967.1 centromere protein K isoform 1
NM_001349367.2 NP_001336296.1 centromere protein K isoform 3
NM_001349368.2 NP_001336297.1 centromere protein K isoform 4
NM_001349369.2 NP_001336298.1 centromere protein K isoform 5
NM_022145.5 NP_071428.2 centromere protein K isoform 1

CENPK Protein Structure

CENP-K

CENP-K: Centromere-associated protein K (2 - 269)

  • 0
  • 100
  • 200
  • 269 a.a.
Protein Preferred Names Protein Names

centromere protein K

SoxLZ/Sox6-binding protein Solt

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02483 CENPK Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CENPK VGNC VGNC:60756
Canis familiaris CENPK VGNC VGNC:39106
Rattus norvegicus CENPK RGD RGD:1310461
Bos taurus CENPK VGNC VGNC:27179
Macaca mulatta CENPK VGNC VGNC:71136
Mus musculus CENPK MGD MGI:1926210