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64110

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11

Inhibitors & Agonists

1

Peptides

2

Inhibitory Antibodies

7

Antibodies

8

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P11077
    LR-17

    TLT-1 (94-110)

    		 TREM receptor Inflammation/Immunology
    LR-17 (TLT-1 (94-110)), a 17-aa peptide, is a TREM-1 inhibitor. LR-17 shows anti-inflammatory effects that can reduce the secretion of pro-inflammatory cytokines induced by Lipopolysaccharides (HY-D1056) (LPS). LR-17 can be used for the study of sepsis .
    LR-17
  • HY-P991135
    Enzelkitug

    RO-7502175; RG-6411

    		 CCR Cancer
    Enzelkitug is a humanized immunoglobulin G1-κ monoclonal antibody targeting the human C-C motif chemokine receptor 8 (CCR8). Enzelkitug is promising for research of various solid tumors and hematological malignancies .
    Enzelkitug
  • HY-RI03417A
    mmu-miR-6410 antagomir

    		MicroRNA Cancer
    mmu-miR-6410 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6410 antagomir
    mmu-miR-6410 antagomir
  • HY-R03418
    mmu-miR-6411 mimic

    		MicroRNA Cancer
    mmu-miR-6411 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-6411 mimic
    mmu-miR-6411 mimic
  • HY-R03418A
    mmu-miR-6411 agomir

    		MicroRNA Cancer
    mmu-miR-6411 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6411 agomir
    mmu-miR-6411 agomir
  • HY-R03417
    mmu-miR-6410 mimic

    		MicroRNA Cancer
    mmu-miR-6410 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-6410 mimic
    mmu-miR-6410 mimic
  • HY-RI03417
    mmu-miR-6410 inhibitor

    		MicroRNA Cancer
    mmu-miR-6410 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-6410 inhibitor
    mmu-miR-6410 inhibitor
  • HY-RI03418
    mmu-miR-6411 inhibitor

    		MicroRNA Cancer
    mmu-miR-6411 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-6411 inhibitor
    mmu-miR-6411 inhibitor
  • HY-R03417A
    mmu-miR-6410 agomir

    		MicroRNA Cancer
    mmu-miR-6410 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6410 agomir
    mmu-miR-6410 agomir
  • HY-RI03418A
    mmu-miR-6411 antagomir

    		MicroRNA Cancer
    mmu-miR-6411 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6411 antagomir
    mmu-miR-6411 antagomir
  • HY-P991135A
    Enzelkitug (FUT8-KO)

    RO-7502175 (FUT8-KO); RG-6411 (FUT8-KO)

    		 CCR Cancer
    Enzelkitug (RO-7502175; RG-6411) (FUT8-KO) is an anti-CCR8 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the antibody-dependent cellular cytotoxicity (ADCC) effect of the antibody. Enzelkitug (FUT8-KO) can be used for the research of various solid tumors and hematological malignancies .
    Enzelkitug (FUT8-KO)

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