Casp2 - caspase 2 Gene
Species: Rattus norvegicus
About Casp2
This gene has 2 transcripts (splice variants), 215 orthologues, 12 paralogues and is associated with 6 phenotypes. Biased expression in Thymus (RPKM 234.6), Spleen (RPKM 136.1) and 9 other tissues.
Summary
Predicted to enable cysteine-type endopeptidase activity involved in apoptotic process; identical protein binding activity; and protein domain specific binding activity. Involved in several processes, including aging; animal organ development; and positive regulation of neuron apoptotic process. Located in membrane and mitochondrion. Biomarker of status epilepticus. Orthologous to human CASP2 (Caspase 2). [provided by Alliance of Genome Resources, Apr 2022]
Casp2 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_022522.3 | NP_071967.2 | caspase-2 |
Casp2 Protein Structure
CARD_CASP2: cd08332 (31 - 117)
CASc: smart00115 (191 - 464)
- 0
- 100
- 200
- 300
- 400
- 470 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
caspase-2 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-P0227 | SHU 9119 | 99.83% | Unkown | |
| HY-P1208 | PG-931 | Agonist | 99.60% | Unkown |
| HY-RS01949 | CASP2 Human Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01950 | Casp2 Mouse Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01951 | Casp2 Rat Pre-designed siRNA Set A | / | Unkown |
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