Golga2 - golgin A2 Gene

Also Known as Gm130

Species: Rattus norvegicus

Gene Type: protein coding

Gene ID: 64528

Summary

Enables importin-alpha family protein binding activity and protein kinase binding activity. Involved in several processes, including Golgi disassembly; mitotic spindle assembly; and protein homotetramerization. Located in Golgi apparatus and neuronal cell body. Part of protein-containing complex. Orthologous to several human genes including GOLGA2 (golgin A2). [provided by Alliance of Genome Resources, Apr 2022]

Golga2 Products (1)

mRNA	Protein	Name
NM_022596.2	NP_072118.2	golgin subfamily A member 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables importin-alpha family protein binding	IDA IDA: Inferred from direct assay	26165940	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	9150144	RGD
enables protein kinase binding	IPI IPI: Inferred from physical interaction	9753325	RGD
enables protein-containing complex binding	IDA IDA: Inferred from direct assay	11927603	RGD

Biological Process GO Annotation	Evidence	References	Source
involved in Golgi disassembly	IDA IDA: Inferred from direct assay	9753325	RGD
involved in endoplasmic reticulum to Golgi vesicle-mediated transport	IDA IDA: Inferred from direct assay	10679020	RGD
involved in mitotic spindle assembly	IMP IMP: Inferred from mutant phenotype	26165940	RGD
involved in protein homotetramerization	IDA IDA: Inferred from direct assay	25787021	RGD

Cellular Component GO Annotation	Evidence	References	Source
located in Golgi apparatus	IDA IDA: Inferred from direct assay	8315394	RGD
located in Golgi cis cisterna	IDA IDA: Inferred from direct assay	8557739	RGD
located in Golgi cisterna membrane	IDA IDA: Inferred from direct assay	9150144	RGD
located in cis-Golgi network	IDA IDA: Inferred from direct assay	19474315	RGD
located in neuronal cell body	IDA IDA: Inferred from direct assay	16421253	RGD
part of protein-containing complex	IDA IDA: Inferred from direct assay	11927603	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
golgin subfamily A member 2	130 kDa cis-Golgi matrix protein cis-Golgi matrix protein GM130 golgi autoantigen, golgin subfamily a, 2

Golga2 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	Golga2	Q62839	Gorasp1	Rattus norvegicus	O35254	Anti Bait CoIP	11739401
Cross	Golga2	Q62839	Zfpl1	Mus musculus	Q9DB43	Density Sedimentation	18323775
Cross	Golga2	Q62839	Zfpl1	Mus musculus	Q9DB43	Anti Tag CoIP	18323775
Cross	Golga2	Q62839	Zfpl1	Mus musculus	Q9DB43	Crosslink	18323775
Cross	Golga2	Q62839	Zfpl1	Mus musculus	Q9DB43	Y2H	18323775
Cross	Golga2	Q62839	Zfpl1	Mus musculus	Q9DB43	Pull Down	18323775
Cross	Golga2	Q62839	Zfpl1	Mus musculus	Q9DB43	Anti Bait CoIP	18323775

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05583	GOLGA2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Golga2	NCBI	NCBI:2801