Krt20 - keratin 20 Gene

Also Known as K20; Ck20; Ck-20; Krt21; 9030623C06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66809

About Krt20

Chromosome 11: 99,319,229-99,328,976 reverse strand.GRCm39:CM001004.3

This gene has 1 transcript (splice variant), 103 orthologues and 69 paralogues. Biased expression in large intestine adult (RPKM 276.4), small intestine adult (RPKM 251.1) and 5 other tissues.

Summary

This gene encodes a member of the keratin protein family and is found within a cluster of cytokeratin genes on chromosome 11. Keratins are cytoskeletal proteins that are preferentially expressed in epithelial cells. The encoded protein may help maintain intermediate filament organization in intestinal epithelium. Phosphorylation of this protein may also influence Mucin secretion in the small intestine. [provided by RefSeq, Dec 2015]

Krt20 Products (1)

mRNA Protein Name
NM_023256.2 NP_075745.1 keratin, type I cytoskeletal 20

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12857878 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular response to starvation IDA
IDA: Inferred from direct assay
16608857 MGI
involved in intermediate filament organization IMP
IMP: Inferred from mutant phenotype
12857878 MGI
involved in regulation of protein secretion IDA
IDA: Inferred from direct assay
16608857 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Krt20 Protein Structure

Filament

Filament: pfam00038 (75 - 384)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 431 a.a.
Protein Preferred Names Protein Names

keratin, type I cytoskeletal 20

  • cytokeratin 20

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07444 KRT20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07445 Krt20 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07446 Krt20 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Krt20 NCBI NCBI:54474