Brpf1 - bromodomain and PHD finger containing, 1 Gene

Rattus norvegicus

Gene ID: 679713 | Gene type: protein coding

About Brpf1

Primary_assembly 4: 146,456,318-146,472,649 forward strand.mRatBN7.2:CM026977.1

This gene has 1 transcript (splice variant), 211 orthologues, 8 paralogues and is associated with 12 phenotypes. Biased expression in Thymus (RPKM 11.7), Heart (RPKM 84.1) and 9 other tissues.

Summary

Predicted to enable acetyltransferase activator activity and histone binding activity. Predicted to be involved in histone H3-K14 acetylation; histone H3-K23 acetylation; and positive regulation of transcription, DNA-templated. Predicted to act upstream of or within common myeloid progenitor cell proliferation; regulation of fibroblast proliferation; and tube morphogenesis. Predicted to be located in cytosol; nucleus; and plasma membrane. Predicted to be part of MOZ/MORF Histone Acetyltransferase complex. Orthologous to human BRPF1 (bromodomain and PHD finger containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Brpf1 Products(1)

mRNA	Protein	Name
NM_001191572.1	NP_001178501.1	peregrin

Brpf1 Protein Structure

SFP1

COG5141

ePHD_BRPF1

Bromo_brd1_like

PWWP_BRPF1

0
200
400
600
800
1000
1252 a.a.

Protein Preferred Names

Protein Names

peregrin

Related Agents

Pre-clinical Phase

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-107424	BAY-299	Inhibitor	99.24%	Unkown
HY-100729	GSK9311	Inhibitor	99.52%	Unkown
HY-130622	LT052	Inhibitor	98.77%	Unkown
HY-100729A	GSK9311 hydrochloride	Inhibitor	/	Unkown
HY-151366	HDAC8/BRPF1-IN-1	Inhibitor	/	Unkown
HY-143332	TRIM24/BRPF1-IN-2	Inhibitor	/	Unkown
HY-149806	Bromodomain IN-2	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Brpf1	NCBI	NCBI:7862

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