Brpf1 - bromodomain and PHD finger containing, 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 679713

About Brpf1

Primary_assembly 4: 146,456,318-146,472,649 forward strand.mRatBN7.2:CM026977.1

This gene has 1 transcript (splice variant), 211 orthologues, 8 paralogues and is associated with 12 phenotypes. Biased expression in Thymus (RPKM 11.7), Heart (RPKM 84.1) and 9 other tissues.

Summary

Predicted to enable acetyltransferase activator activity and histone binding activity. Predicted to be involved in histone H3-K14 acetylation; histone H3-K23 acetylation; and positive regulation of transcription, DNA-templated. Predicted to act upstream of or within common myeloid progenitor cell proliferation; regulation of fibroblast proliferation; and tube morphogenesis. Predicted to be located in cytosol; nucleus; and plasma membrane. Predicted to be part of MOZ/MORF Histone Acetyltransferase complex. Orthologous to human BRPF1 (bromodomain and PHD finger containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Brpf1 Products (1)

mRNA Protein Name
NM_001191572.1 NP_001178501.1 peregrin

Brpf1 Protein Structure

SFP1

SFP1: cl25788 (19 - 49)

COG5141

COG5141: cl34917 (172 - 655)

ePHD_BRPF1

ePHD_BRPF1: cd15701 (328 - 448)

Bromo_brd1_like

Bromo_brd1_like: cd05512 (630 - 733)

PWWP_BRPF1

PWWP_BRPF1: cd20156 (1120 - 1239)

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  • 1252 a.a.
Protein Preferred Names Protein Names

peregrin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-107424 BAY-299 Inhibitor 99.40% Unkown
HY-130622 LT052 Inhibitor 98.02% Unkown
HY-100729 GSK9311 Inhibitor 99.33% Unkown
HY-143332 TRIM24/BRPF1-IN-2 Inhibitor 98.74% Unkown
HY-101121 NI-42 Inhibitor 99.53% Unkown
HY-100729A GSK9311 hydrochloride Inhibitor / Unkown
HY-149806 Bromodomain IN-2 Inhibitor / Unkown
HY-151366 HDAC8/BRPF1-IN-1 Inhibitor / Unkown
HY-122626 BRPF1B/TRIM24-IN-1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Brpf1 NCBI NCBI:7862