Tmem97 - transmembrane protein 97 Gene

Also Known as D11Bhm182e; 1810014L12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69071

About Tmem97

Chromosome 11: 78,432,643-78,441,603 reverse strand.GRCm39:CM001004.3

This gene has 1 transcript (splice variant), 200 orthologues and is associated with 3 phenotypes. Broad expression in testis adult (RPKM 26.9), liver E18 (RPKM 37.6) and 15 other tissues.

Summary

Predicted to be involved in Cholesterol homeostasis. Predicted to be located in several cellular components, including lysosome; nuclear membrane; and rough endoplasmic reticulum. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; central nervous system; limb; male reproductive gland or organ; and skeleton. Orthologous to human TMEM97 (transmembrane protein 97). [provided by Alliance of Genome Resources, Apr 2022]

Tmem97 Products (1)

mRNA Protein Name
NM_133706.2 NP_598467.1 sigma intracellular receptor 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Referencias Source
enables oxysterol binding IMP
IMP: Inferred from mutant phenotype
34799735 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Tmem97 Protein Structure

EBP

EBP: pfam05241 (42 - 149)

  • 0
  • 100
  • 176 a.a.
Protein Preferred Names Protein Names

sigma intracellular receptor 2

  • sigma-2 receptor

  • sigma2 receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-117731 UKH-1114 Agonist 99.88% Unkown
HY-RS14750 TMEM97 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14751 Tmem97 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14752 Tmem97 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmem97 NCBI NCBI:27346