Tmem97 - transmembrane protein 97 Gene

Also Known as D11Bhm182e; 1810014L12Rik

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 69071

About Tmem97

Chromosome 11: 78,432,643-78,441,603 reverse strand.GRCm39:CM001004.3

This gene has 1 transcript (splice variant), 200 orthologues and is associated with 3 phenotypes. Broad expression in testis adult (RPKM 26.9), liver E18 (RPKM 37.6) and 15 other tissues.

Summary

Predicted to be involved in Cholesterol homeostasis. Predicted to be located in several cellular components, including lysosome; nuclear membrane; and rough endoplasmic reticulum. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; central nervous system; limb; male reproductive gland or organ; and skeleton. Orthologous to human TMEM97 (transmembrane protein 97). [provided by Alliance of Genome Resources, Apr 2022]

Tmem97 Products (1)

mRNA Protein Name
NM_133706.2 NP_598467.1 sigma intracellular receptor 2
Molecular Function GO Annotation Evidence 参考文献 由来
enables oxysterol binding IMP
IMP: Inferred from mutant phenotype
34799735 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Tmem97 Protein Structure

EBP

EBP: pfam05241 (42 - 149)

  • 0
  • 100
  • 176 a.a.
Protein Preferred Names Protein Names

sigma intracellular receptor 2

  • sigma-2 receptor

  • sigma2 receptor

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Tmem97 NCBI NCBI:27346