TEP1 - telomerase associated protein 1 Gene

Homo sapiens

Also known as TP1; TLP1; p240; TROVE1; VAULT2

Gene ID: 7011 | Gene type: protein coding

About TEP1

Cytogenetic location: 14q11.2 Genomic coordinates (GRCh38): 14:20,365,667-20,413,501 (from NCBI)

This gene has 11 transcripts (splice variants), 106 orthologues and 26 paralogues. Ubiquitous expression in duodenum (RPKM 11.6), small intestine (RPKM 7.0) and 24 other tissues.

Summary

This gene product is a component of the ribonucleoprotein complex responsible for Telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

TEP1 Products(2)

mRNA	Protein	Name
NM_001319035.2	NP_001305964.1	telomerase protein component 1 isoform 2
NM_007110.5	NP_009041.2	telomerase protein component 1 isoform 1

TEP1 Protein Structure

TEP1_N

TROVE

DUF4062

NACHT

WD40

0
500
1000
1500
2000
2627 a.a.

Protein Preferred Names

Protein Names

telomerase protein component 1

TROVE domain family, member 1

Related Diseases

Diseases

Alias

Campylobacteriosis

Campylobacter Infections	Campylobacter Infection
Enteric Campylobacteriosis

Gastric Cancer

Stomach Cancer	Gastric Carcinoma
Stomach Carcinoma	Gastric Cancer, Somatic
Gastric Neoplasm	Carcinoma Of Stomach
Stomach Neoplasms	Malignant Neoplasm Of Stomach
Gastric Cancer Risk After H. Pylori Infection	Cancer Of The Stomach
Adult Stomach Cancer	Adult Stomach Carcinoma
GASC	Gastric Cancer Intestinal
Gastric Cancers	Gastric Carcinomas
Cancer, Gastric	Stomach Neoplasm
Malignant Neoplasm Of Body Of Stomach	Malignant Tumor Of Lesser Curve Of Stomach
Gastrocarcinoma Of Unspecified Site	Leather Bottle Stomach
Carcinoma Of Fundus Of Stomach	Cancer Of Fundus Of Stomach
Primary Malignant Neoplasm Of Body Of Stomach	Cancer Of Body Of Stomach
Primary Malignant Neoplasm Of Pyloric Antrum	Pyloric Antrum Cancer
Malignant Tumour Of Stomach

Cerebral Palsy

Infantile Cerebral Palsy	Mixed Cerebral Palsy
Palsy Cerebral	Palsy, Cerebral
Cerebral Palsy, Mixed

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14369	TEP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	TEP1	VGNC	VGNC:35745
Rattus norvegicus	TEP1	RGD	RGD:3869
Felis catus	TEP1	VGNC	VGNC:66079
Macaca mulatta	TEP1	VGNC	VGNC:78310
Canis familiaris	TEP1	VGNC	VGNC:47249
Mus musculus	TEP1	MGD	MGI:109573

Name
Email *

	Sorry, but the email address you supplied was invalid.