Cd248 - CD248 antigen, endosialin Gene

Also Known as Tem1; Cd164l1; 2610111G01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70445

Summary

Enables extracellular matrix binding activity. Acts upstream of or within several processes, including anatomical structure regression; lymph node development; and positive regulation of endothelial cell apoptotic process. Located in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; integumental system; and skeleton. Orthologous to human CD248 (CD248 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd248 Products (1)

mRNA Protein Name
NM_054042.2 NP_473383.1 endosialin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables extracellular matrix binding IDA
IDA: Inferred from direct assay
22740442 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within anatomical structure regression IMP
IMP: Inferred from mutant phenotype
22740442 MGI
acts upstream of endothelial cell apoptotic process IMP
IMP: Inferred from mutant phenotype
22740442 MGI
acts upstream of or within fibroblast migration IMP
IMP: Inferred from mutant phenotype
20432232 MGI
acts upstream of fibroblast proliferation IMP
IMP: Inferred from mutant phenotype
20432232 MGI
acts upstream of or within lymph node development IMP
IMP: Inferred from mutant phenotype
20432232 MGI
acts upstream of or within positive regulation of endothelial cell apoptotic process IMP
IMP: Inferred from mutant phenotype
22740442 MGI
acts upstream of or within positive regulation of fibroblast proliferation IMP
IMP: Inferred from mutant phenotype
20432232 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11489895 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

endosialin

  • CD164 sialomucin-like 1

  • tumor endothelial marker 1

Recombinant Cd248 Proteins

Cat. No. Product Name Accession Purity
HY-P78043 Endosialin/CD248 Protein, Mouse (HEK293, His) Q91V98 (Q18-L695) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99778 Ontuxizumab 99.85% Phase 2

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02215 CD248 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18990 Cd248 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25479 Cd248 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd248 NCBI NCBI:57124