CXCR4 - C-X-C motif chemokine receptor 4 Gene

Macaca mulatta

Gene ID: 707329 | Gene type: protein coding

About CXCR4

Primary_assembly 12: 21,290,540-21,294,377 reverse strand.Mmul_10:CM014347.1

This gene has 3 transcripts (splice variants), 285 orthologues and 24 paralogues.

CXCR4 Products(1)

mRNA	Protein	Name
NM_001042645.1	NP_001036110.1	C-X-C chemokine receptor type 4

CXCR4 Protein Structure

CXCR4_N

7tmA_CXCR4

0
100
200
300
352 a.a.

Protein Preferred Names

Protein Names

C-X-C chemokine receptor type 4

CXC-R4	CXCR-4
LESTR	SDF-1 receptor
chemokine (C-X-C motif) receptor 4	fusin
leukocyte-derived seven transmembrane domain receptor	stromal cell-derived factor 1 receptor

Related Agents

Approval

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-10046	Plerixafor	Antagonist	99.90%	Yes
HY-50912	Plerixafor octahydrochloride	Antagonist	99.09%	Yes
HY-P0171	Motixafortide	Antagonist	99.76%	Unkown
HY-50101A	Mavorixafor trihydrochloride	Antagonist	99.75%	Yes
HY-50101	Mavorixafor	Antagonist	99.72%	Yes
HY-50101C	Mavorixafor hydrochloride	Antagonist	99.64%	Unkown

Clinical Phase

Bioactive Molecules (8)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P1682A	Balixafortide TFA	Antagonist	99.89%	Phase 3
HY-P1682	Balixafortide	Antagonist	98.20%	Phase 3
HY-12488	LY2510924	Inhibitor	99.85%	Phase 2
HY-19867A	Burixafor hydrobromide	Antagonist	/	Phase 2
HY-P1103	CTCE-9908	Antagonist	99.54%	Phase 2
HY-114244	USL311	Antagonist	99.97%	Phase 2
HY-19867	Burixafor	Antagonist	/	Phase 2
HY-13696	MSX-122	Antagonist	98.16%	Phase 1

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99272	Ulocuplumab	Antagonist	99.90%	Phase 3

Pre-clinical Phase

Bioactive Molecules (56)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-N0011	Baohuoside I	Inhibitor	99.94%	Unkown
HY-W087028	NOTA-NHS ester		≥97.0%	Unkown
HY-111793A	NUCC-390 dihydrochloride	Agonist	98.19%	Unkown
HY-101458A	IT1t dihydrochloride	Antagonist	99.77%	Unkown
HY-P3612	CTCE-0214	Agonist	99.96%	Unkown
HY-15478	WZ811	Antagonist	99.80%	Unkown
HY-P1102	TC14012	Modulator	99.77%	Unkown
HY-P1104A	FC131 TFA	Antagonist	99.87%	Unkown
HY-D0976	NF279	Antagonist	98.5%	Unkown
HY-15971A	AMD 3465	Antagonist	98.24%	Unkown
HY-P10415	EPI-X4	Antagonist	99.21%	Unkown
HY-111793	NUCC-390	Agonist	98.40%	Unkown
HY-15971	AMD 3465 hexahydrobromide	Antagonist	98.0%	Unkown
HY-P7061A	ALX 40-4C Trifluoroacetate	Inhibitor	99.78%	Unkown
HY-122058A	KRH-3955 hydrochloride	Antagonist	/	Unkown
HY-161735	CXCR4-IN-3	Inhibitor	99.69%	Unkown
HY-167851	CCX662	Inhibitor	98.62%	Unkown
HY-P0172	ATI-2341	Agonist	99.64%	Unkown
HY-146372	CXCR4 antagonist 5	Antagonist	/	Unkown
HY-146413	HF50731	Antagonist	/	Unkown
HY-P4111A	Peptide R TFA	Antagonist	98.34%	Unkown
HY-P1104	FC131	Antagonist	/	Unkown
HY-147978	CXCR4 antagonist 8	Antagonist	/	Unkown
HY-P7061	ALX 40-4C	Inhibitor	/	Unkown
HY-P10973	Peptide R analogue 10	Antagonist	/	Unkown
HY-P4111	Peptide R	Antagonist	/	Unkown
HY-168095	CXCR4 antagonist 10	Inhibitor	/	Unkown
HY-101458	IT1t	Antagonist	/	Unkown
HY-147979	CXCR4 antagonist 9	Antagonist	/	Unkown
HY-146054	CXCR4 modulator-2	Modulator	/	Unkown
HY-103010	MSX-130	Antagonist	98.00%	Unkown
HY-P10971	Nef-M1	Antagonist	/	Unkown
HY-P11011A	Peptide R54 acetate	Antagonist	/	Unkown
HY-162632	Hit 14	Inhibitor	≥99.0%	Unkown
HY-103009	MSX-127	Antagonist	99.68%	Unkown
HY-136437	CXCR4 antagonist 1	Antagonist	/	Unkown
HY-144286	CXCR4 antagonist 3	Inhibitor	/	Unkown
HY-P10429	RCP168	Antagonist	/	Unkown
HY-178205	BPRCX807	Antagonist	/	Unkown
HY-146053	CXCR4 modulator-1	Modulator	/	Unkown
HY-177799	BPRCX 714	Antagonist	/	Unkown
HY-N9858	Herpetin	Activator	/	Unkown
HY-P1102A	TC14012 TFA	Modulator	/	Unkown
HY-P1103A	CTCE-9908 TFA	Antagonist	/	Unkown
HY-115493	TIQ-15	Antagonist	/	Unkown
HY-144285	CXCR4 antagonist 4	Antagonist	/	Unkown
HY-182850	UCUF-965	Modulator	/	Unkown
HY-148640	WK500B	Activator	/	Unkown
HY-146401	CXCR4 antagonist 6	Antagonist	/	Unkown
HY-P11019	IS4	Antagonist	/	Unkown
HY-129094	ICT5040	Antagonist	/	Unkown
HY-P11451	Pentixather		/	Unkown
HY-147808	CXCR4 antagonist 7	Antagonist	/	Unkown
HY-P11011	Peptide R54	Antagonist	/	Unkown
HY-P10427	DV1	Antagonist	/	Unkown
HY-123819	KRH-1636	Antagonist	/	Unkown

Inhibitory Antibodies (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P991744	Anti-Mouse CXCR4 Antibody (Cx4Mab-1)		/	Unkown
HY-P992439	PF-06747143	Inhibitor	/	Unkown
HY-P992405	MEDI-3185	Antagonist	/	Unkown
HY-P991656	LY-2624587	Antagonist	/	Unkown
HY-P991647	ALX-0651	Inhibitor	/	Unkown
HY-P991568	AT009	Modulator	/	Unkown
HY-P992397	KY1051	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	CXCR4	NCBI	NCBI:7852

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