BPRCX 714
BPRCX 714 is a CXCR4 (CXC chemokine receptor type 4) receptor antagonist. BPRCX 714 can be used for the study of hepatocellular carcinoma.
For research use only. We do not sell to patients.
- CAS No.: 1892574-13-8
- Formula: C30H51N11O3
- Molecular Weight:613.80
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
CXCR4 |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Detroit 551 | CC50 |
100 μM
Compound: 16
|
Cytotoxicity against human Detroit 551 cells
Cytotoxicity against human Detroit 551 cells
|
[PMID: 29314840] |
In Vitro
Chemical Information
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CAS No. 1892574-13-8
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Molecular Weight 613.80
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Formula C30H51N11O3
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SMILES
O=C(O)CNCCC(N1CCC(NC2=NC(NCC3=CN(CCCNCCCNC4CCCCC4)N=N3)=NC(C)=C2)CC1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Liver Cancer Modeling
Liver cancer can be classified into primary liver cancer and secondary liver cancer. Secondary liver cancer is the metastatic liver cancer. Primary liver cancer includes hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and fibrolamellar HCC, of which HCC is the most common form, accounting for approximately 90% of primary liver cancers[1]. HCC mouse models include chemical agent-induced models, transplanted tumor models, and genetic engineered models.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)