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Cat. No.: HY-177799

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BPRCX 714

BPRCX 714 is a CXCR4 (CXC chemokine receptor type 4) receptor antagonist. BPRCX 714 can be used for the study of hepatocellular carcinoma.

For research use only. We do not sell to patients.

CAS No.: 1892574-13-8
Formula: C₃₀H₅₁N₁₁O₃
Molecular Weight:613.80

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

BPRCX 714 Chemical Structure

CAS No.: 1892574-13-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

BPRCX 714 is a CXCR4 (CXC chemokine receptor type 4) receptor antagonist. BPRCX 714 can be used for the study of hepatocellular carcinoma^[1].

IC₅₀ & Target^[1]

CXCR4

All CXCR Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
Detroit 551	CC₅₀	100 μM Compound: 16	Cytotoxicity against human Detroit 551 cells Cytotoxicity against human Detroit 551 cells	[PMID: 29314840]

In Vitro

BPRCX714 exhibits inhibitory effects on the CXCR4 receptor in CCRF-CEM cells with an IC₅₀ of 34.2 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1892574-13-8
Molecular Weight 613.80
Formula C₃₀H₅₁N₁₁O₃
SMILES

O=C(O)CNCCC(N1CCC(NC2=NC(NCC3=CN(CCCNCCCNC4CCCCC4)N=N3)=NC(C)=C2)CC1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Song JS, et al. A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2015433118. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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BPRCX 714

All CXCR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BPRCX 714 Related Classifications

HY-177799 Related Classifications