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Cat. No.: HY-136437

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CXCR4 antagonist 1

CXCR4 antagonist 1 is a potent CXCR4 antagonist. CXCR4 antagonist 1 has anti-HIV activity.

For research use only. We do not sell to patients.

CAS No.: 675135-69-0
Formula: C₂₇H₄₃N₇
Molecular Weight:465.68

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

CXCR4 antagonist 1 Chemical Structure

CAS No.: 675135-69-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

CXCR4 antagonist 1 is a potent CXCR4 antagonist. CXCR4 antagonist 1 has anti-HIV activity^[1].

IC₅₀ & Target^[1]

HIV-1

CXCR4

All CXCR Isoforms :

All HIV Isoforms :

In Vitro

HIV-1 entry is triggered by interaction of gp120 with CD4 and chemokine receptors (CKRs), such as CCR5 and CXCR4^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 675135-69-0
Molecular Weight 465.68
Formula C₂₇H₄₃N₇
SMILES

CCCN(CCC)CCCCNCC1=CC=C(CN(CC2=NC=CN2)CC3=NC=CN3C)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yuta Hikichi, et al. Increased HIV-1 Sensitivity to Neutralizing Antibodies by Mutations in the Env V3-coding Region for Resistance to CXCR4 Antagonists. J Gen Virol. 2016 Sep;97(9):2427-2440. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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CXCR4 antagonist 1

All CXCR Isoforms

All HIV Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

CXCR4 antagonist 1 Related Classifications

HY-136437 Related Classifications