CXCR4 antagonist 6

CXCR4 antagonist 6 (compound 46) is a potent CXCR4 antagonist with an IC50 value of 79 nM. CXCR4 antagonist 6 inhibits CXCL12 induced cytosolic calcium flux (IC50 = 0.25 nM). CXCR4 antagonist 6 significantly mitigates CXCL12/CXCR4 mediated cell migration. CXCR4 antagonist 6 exhibits marked efficacy in a cancer metastasis model in mice.

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  • CAS No.: 2304750-68-1
  • Formula: C21H30N6
  • Molecular Weight:366.50
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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