CXCR4 modulator-2
CXCR4 modulator-2 (compound Z7R) is a highly potent CXCR4 modulator with an IC50 value of 1.25 nM. CXCR4 modulator-2 has acceptable stability (t1/2 = 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 95.0%
- CAS 番号: 2554877-43-7
- 分子式: C21H32N8O2
- 分子量:428.53
-
保管条件:
4°C, protect from light, stored under argon
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under argon)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
|
CXCR4 1.25 nM (IC50) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:male nude mice (6 weeks, 20 g; subcutaneous injection of 50 μL of λ-carrageenan)[1]
-
Dosage:10 mg/kg
-
Administration:IP; single dosage
-
Result:Significantly reduced the edema weights (∼50%) in the lesion and decreased the expression of CXCR4s.
化学情報
-
CAS 番号 2554877-43-7
-
性状 Solid
-
分子量 428.53
-
分子式 C21H32N8O2
-
SMILES
O=C(NC1CCN(C(CCN2C=CC3=C2C=NC=C3)=O)CC1)[C@@H](N)CCCNC(N)=N
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
4°C, protect from light, stored under argon
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under argon)
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
CXCR4 modulator-2 関連分類
HY-146054 関連分類
Powered by Bioz