MSX-127
Based on 1 publication(s) in Google Scholar
MSX-127 is a CXCR4 antagonist. MSX-127 inhibits cancer metastasis.
For research use only. We do not sell to patients.
- Purity: 99.68%
- CAS No.: 6616-56-4
- Formula: C16H24N2O4
- Molecular Weight:308.37
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) MSX-127
More
Biological Activity
|
CXCR4 |
The C-X-C chemokine receptor-4 (CXCR4) is a seven trans-membrane G-protein coupled receptor (GPCR) classified as a member of the family I GPCR or rhodopsin-like GPCR family. CXCR4 plays an important role in cancer metastasis, regulation of stem cell trafficking, and neovascularization[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 6616-56-4
-
Appearance Solid
-
Molecular Weight 308.37
-
Formula C16H24N2O4
-
Color White to off-white
-
SMILES
OC1=CC(CN2CCOCC2)=C(O)C=C1CN3CCOCC3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Cell Biol Int
2022 Sep;46(9):1519-1529. PMID: 35731168
Solvent & Solubility
DMSO : 41.67 mg/mL (135.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2429 mL | 16.2143 mL | 32.4286 mL | 81.0714 mL |
| 5 mM | 0.6486 mL | 3.2429 mL | 6.4857 mL | 16.2143 mL | |
| 10 mM | 0.3243 mL | 1.6214 mL | 3.2429 mL | 8.1071 mL | |
| 15 mM | 0.2162 mL | 1.0810 mL | 2.1619 mL | 5.4048 mL | |
| 20 mM | 0.1621 mL | 0.8107 mL | 1.6214 mL | 4.0536 mL | |
| 25 mM | 0.1297 mL | 0.6486 mL | 1.2971 mL | 3.2429 mL | |
| 30 mM | 0.1081 mL | 0.5405 mL | 1.0810 mL | 2.7024 mL | |
| 40 mM | 0.0811 mL | 0.4054 mL | 0.8107 mL | 2.0268 mL | |
| 50 mM | 0.0649 mL | 0.3243 mL | 0.6486 mL | 1.6214 mL | |
| 60 mM | 0.0540 mL | 0.2702 mL | 0.5405 mL | 1.3512 mL | |
| 80 mM | 0.0405 mL | 0.2027 mL | 0.4054 mL | 1.0134 mL | |
| 100 mM | 0.0324 mL | 0.1621 mL | 0.3243 mL | 0.8107 mL |