CASR - calcium sensing receptor Gene

Species: Macaca mulatta

Gene Type: protein coding
Gene ID: 714441

About CASR

Primary_assembly 2: 154,032,428-154,133,319 reverse strand.Mmul_10:CM014337.1

This gene has 2 transcripts (splice variants), 203 orthologues and 4 paralogues.

CASR Products (3)

mRNA Protein Name
XM_028844591.1 XP_028700424.1 extracellular calcium-sensing receptor
XM_028844592.1 XP_028700425.1 extracellular calcium-sensing receptor
XM_015129990.2 XP_014985476.2 extracellular calcium-sensing receptor

CASR Protein Structure

PBP1_CaSR

PBP1_CaSR: cd06364 (32 - 529)

NCD3G

NCD3G: pfam07562 (537 - 590)

7tmC_CaSR

7tmC_CaSR: cd15282 (610 - 861)

7tmC_CaSR

7tmC_CaSR: cd15282 (610 - 635)

7tmC_CaSR

7tmC_CaSR: cd15282 (647 - 668)

7tmC_CaSR

7tmC_CaSR: cd15282 (677 - 701)

7tmC_CaSR

7tmC_CaSR: cd15282 (725 - 741)

7tmC_CaSR

7tmC_CaSR: cd15282 (768 - 794)

7tmC_CaSR

7tmC_CaSR: cd15282 (802 - 825)

7tmC_CaSR

7tmC_CaSR: cd15282 (830 - 855)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1078 a.a.
Protein Preferred Names Protein Names

extracellular calcium-sensing receptor

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-70037 Cinacalcet Agonist 99.93% Yes
HY-70037A Cinacalcet hydrochloride Agonist 99.98% Yes
HY-P1955A Etelcalcetide hydrochloride Activator 99.80% Unkown
HY-17397 Strontium Ranelate Activator 99.30% Unkown
HY-17613 Evocalcet Activator 99.28% Unkown
HY-109106A Upacicalcet sodium Agonist 99.91% Unkown
HY-P1955 Etelcalcetide Activator / Unkown
HY-109106 Upacicalcet Agonist / Unkown

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-10007 NPS-2143 Antagonist 99.94% Phase 2
HY-10167A Tecalcet Hydrochloride Modulator 99.43% Phase 2

Pre-clinical Phase

Bioactive Molecules (45)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-139201A Poly-D-lysine hydrobromide (MW 70000-150000) Agonist 99.86% Unkown
HY-139201 Poly-D-lysine hydrobromide (MW 30000-70000) Agonist / Unkown
HY-112171 γ-L-Glutamyl-L-alanine Modulator 98.0% Unkown
HY-12557 γ-Glutamylvaline Agonist 99.94% Unkown
HY-10171 NPS-2143 hydrochloride Antagonist 99.98% Unkown
HY-103320A Calhex 231 hydrochloride Inhibitor 99.81% Unkown
HY-N0546 Ligustroflavone Antagonist 99.90% Unkown
HY-139201B Poly-D-lysine hydrobromide (MW 84000) Agonist / Unkown
HY-11095 NPS 2390 Inhibitor 99.90% Unkown
HY-14401 Encaleret Antagonist 99.88% Unkown
HY-122819 Calindol hydrochloride Agonist 99.64% Unkown
HY-121584 Lycoperodine-1 Agonist 99.82% Unkown
HY-139201D Poly-D-lysine hydrobromide (MW 4000-15000) / Unkown
HY-W843885 H-Glu-Thr-OH Activator 98.63% Unkown
HY-P4376A Gamma-Glu-Abu TFA Agonist 96.83% Unkown
HY-103320B (1R,2R)-Calhex 231 hydrochloride Control 98.45% Unkown
HY-117851 AC-265347 Agonist 99.97% Unkown
HY-112171R γ-L-Glutamyl-L-alanine (Standard) Modulator 99.29% Unkown
HY-50713 Calcium-Sensing receptor antagonist I Antagonist 98.95% Unkown
HY-139201E Poly-D-lysine hydrobromide (MW 150000-300000) Agonist / Unkown
HY-107773 GSK3004774 Agonist 99.09% Unkown
HY-139201H Poly-D-lysine hydrobromide (MW ≥300000) Activator / Unkown
HY-15105 SB-423562 Antagonist 99.66% Unkown
HY-15104 Ronacaleret hydrochloride Antagonist 99.81% Unkown
HY-70037AS Cinacalcet-d3 hydrochloride Agonist 97.63% Unkown
HY-W777503 Calindol hydrochloride-13C,D2 / Unkown
HY-P11832 CaSR agonist peptide-1 Agonist / Unkown
HY-153258 CaSR antagonist-1 Antagonist / Unkown
HY-103320 Calhex 231 Antagonist / Unkown
HY-15106 SB-423557 Antagonist / Unkown
HY-14752 Ronacaleret Antagonist / Unkown
HY-10167 Tecalcet Modulator / Unkown
HY-179475 KP-2067 Agonist / Unkown
HY-177303 AXT-914 Inhibitor 98.83% Unkown
HY-P11668 Gosicalcetide Agonist / Unkown
HY-109106B (Rac)-Upacicalcet 95.0% Unkown
HY-139201C Poly-D-lysine hydrobromide (MW 1000-5000) Activator / Unkown
HY-70037S Cinacalcet-d3 Agonist / Unkown
HY-P4376 Gamma-Glu-Abu Agonist / Unkown
HY-14401B Encaleret sodium Antagonist / Unkown
HY-161113 Z8554052021 Activator / Unkown
HY-17613S Evocalcet-d4 Activator / Unkown
HY-W653978 Cinacalcet-d4 hydrochloride Agonist / Unkown
HY-182543 NPS-467 Activator / Unkown
HY-171446 TAK-075 Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CASR NCBI NCBI:846