EIF3CL - eukaryotic translation initiation factor 3 subunit C like Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 728689

Summary

The protein encoded by this gene is a core subunit of the eukaryotic translation initiation factor 3 (eIF3) complex. The encoded protein is nearly identical to another protein, eIF3c, from a related gene. The eIF3 complex binds the 40S ribosome and mRNAs to enable translation initiation. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015]
Ubiquitous expression in ovary (RPKM 103.1), thyroid (RPKM 97.8) and 25 other tissues.

EIF3CL Products (3)

mRNA Protein Name
NM_001099661.2 NP_001093131.1 eukaryotic translation initiation factor 3 subunit C-like protein
NM_001317856.1 NP_001304785.1 eukaryotic translation initiation factor 3 subunit C-like protein
NM_001317857.2 NP_001304786.1 eukaryotic translation initiation factor 3 subunit C-like protein

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EIF3CL Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
EIF3CL B5ME19 EIF3H Homo sapiens O15372
Crosslink
30021884
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04259 EIF3C Human Pre-designed siRNA Set A Pre-designed Set / Unkown