PLIN4 - perilipin 4 Gene

Also Known as S3-12; KIAA1881

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 729359

About PLIN4

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:4,502,192-4,518,486 (from NCBI)

This gene has 2 transcripts (splice variants), 155 orthologues and 4 paralogues. Biased expression in fat (RPKM 510.0) and heart (RPKM 14.4).

Summary

Members of the perilipin family, such as PLIN4, coat intracellular lipid storage droplets (Wolins et al., 2003 [PubMed 12840023]).[supplied by OMIM, Feb 2010]

PLIN4 Products (5)

mRNA Protein Name
NM_001367868.2 NP_001354797.1 perilipin-4 isoform 2
NM_001393888.1 NP_001380817.1 perilipin-4 isoform 1
NM_001393889.1 NP_001380818.1 perilipin-4 isoform 1
NM_001393890.1 NP_001380819.1 perilipin-4 isoform 2
NM_001393891.1 NP_001380820.1 perilipin-4 isoform 2

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in lipid droplet IDA
IDA: Inferred from direct assay
21498505 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PLIN4 Protein Structure

Perilipin

Perilipin: Perilipin family (67 - 146)

Perilipin

Perilipin: Perilipin family (1145 - 1336)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1357 a.a.
Protein Preferred Names Protein Names

perilipin-4

  • adipocyte protein S3-12

Related Diseases

Diseases Alias
Chicken Egg Allergy

  • Gallus Gallus Egg Allergy
Ichthyosis, Congenital, Autosomal Recessive 3

  • Autosomal Recessive Congenital Ichthyosis 3

  • ARCI3

  • Lamellar Ichthyosis 5

  • Collodion Baby, Self-Healing

  • Ichthyosis, Lamellar, 5, Formerly

  • Li5, Formerly

  • Li5

  • Self-Healing Collodion Baby

  • Ichthyosis, Congenital, Autosomal Recessive, Type 3
Chanarin-Dorfman Syndrome

  • Neutral Lipid Storage Disease

  • CDS

  • Neutral Lipid Storage Disease With Ichthyosis

  • Triglyceride Storage Disease With Impaired Long-Chain Fatty Acid Oxidation

  • Triglyceride Storage Disease With Ichthyosis

  • Nlsdi

  • Ichthyotic Neutral Lipid Storage Disease

  • Dorfman-Chanarin Syndrome

  • Dcs

  • Chanarin-Dorfman Disease

  • Ichthyosiform Erythroderma With Leukocyte Vacuolation

  • Lipidosis With Triglyceride Storage Disease

  • Disorder Of Cornification 12

  • Dorfman Chanarin Syndrome

  • Neutral Lipid Storage Disease With Ichthyotic

  • Dorfman-Chanarin Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10709 PLIN4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29447 Plin4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus PLIN4 MGD MGI:1929709
Canis familiaris PLIN4 VGNC VGNC:44693
Bos taurus PLIN4 VGNC VGNC:55299
Felis catus PLIN4 VGNC VGNC:64242
Rattus norvegicus PLIN4 RGD RGD:1590867
Macaca mulatta PLIN4 VGNC VGNC:84900
Others PLIN4 NCBI