ZNF175 - zinc finger protein 175 Gene

Also Known as OTK18

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 7728

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Located in cytosol and nucleolus. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in thyroid (RPKM 3.4), ovary (RPKM 3.2) and 25 other tissues.

ZNF175 Products (1)

mRNA Protein Name
NM_007147.4 NP_009078.1 zinc finger protein 175

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
17170456 GOA
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
17170456 GOA
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
17170456 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
17170456 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
17170456 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF175 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
ZNF175 Q9Y473 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
25416956
Intra
ZNF175 Q9Y473 KRTAP10-7 Homo sapiens P60409
Validated Y2H
25416956
Intra
ZNF175 Q9Y473 ZNF250 Homo sapiens P15622-3
Y2H Array
25416956
Intra
ZNF175 Q9Y473 ZNF264 Homo sapiens Q14C61
Validated Y2H
25416956
Intra
ZNF175 Q9Y473 ALAS1 Homo sapiens P13196
Validated Y2H
25416956
Intra
ZNF175 Q9Y473 ALAS1 Homo sapiens P13196
Y2H Array
25416956
Intra
ZNF175 Q9Y473 ALAS1 Homo sapiens P13196
Y2H Array
32296183
Intra
ZNF175 Q9Y473 ALAS1 Homo sapiens P13196
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS16106 ZNF165 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16107 ZNF185 Human Pre-designed siRNA Set A Pre-designed Set / Unkown