LUZP1 - leucine zipper protein 1 Gene

Also Known as LUZP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 7798

About LUZP1

Cytogenetic location: 1p36.12 Genomic coordinates (GRCh38): 1:23,083,642-23,178,122 (from NCBI)

This gene has 4 transcripts (splice variants), 201 orthologues, 3 paralogues and is associated with 1 phenotype. Ubiquitous expression in small intestine (RPKM 10.5), duodenum (RPKM 8.9) and 25 other tissues.

Summary

This gene encodes a protein that contains a leucine zipper motif. The exact function of the encoded protein is not known. In mice this gene affects neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

LUZP1 Products (4)

mRNA Protein Name
NM_001142546.4 NP_001136018.1 leucine zipper protein 1
NM_001395461.1 NP_001382390.1 leucine zipper protein 1
NM_001395462.2 NP_001382391.1 leucine zipper protein 1
NM_033631.5 NP_361013.3 leucine zipper protein 1
Protein Preferred Names Protein Names

leucine zipper protein 1

LUZP1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
LUZP1 Q86V48 YWHAE Homo sapiens P62258
Crosslink
36931259
Intra
LUZP1 Q86V48 DAPK3 Homo sapiens O43293
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Chromosome 1p36 Deletion Syndrome

  • 1p36 Deletion Syndrome

  • Deletion 1p36

  • Monosomy 1p36

  • Subtelomeric 1p36 Deletion

  • Monosomy 1p36 Syndrome

  • Distal Monosomy 1p36

  • Del(1)(P36)

  • Deletion 1pter

  • Monosomy 1pter
Townes-Brocks Syndrome

  • Townes Syndrome

  • Renal-Ear-Anal-Radial Syndrome

  • Anus, Imperforate, With Hand, Foot And Ear Anomalies

  • Imperforate Anus-Hand, Foot And Ear Anomalies Syndrome

  • Rear Syndrome

  • Sensorineural Deafness With Imperforate Anus And Hypoplastic Thumbs

  • Tbs

  • Deafness, Sensorineural, With Imperforate Anus And Hypoplastic Thumbs

  • Imperforate Anus With Hand, Foot And Ear Anomalies

  • Anal-Ear-Renal-Radial Malformation Syndrome

  • Deafness-Imperforate Anus-Hypoplastic Thumbs Syndrome

  • Imperforate Anus-Hand And Foot Anomalies Syndrome

  • Sensorineural Deafness-Imperforate Anus-Hypoplastic Thumbs Syndrome

  • Sensorineural Hearing Loss With Imperforate Anus And Hypoplastic Thumbs
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07892 LUZP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus LUZP1 VGNC VGNC:63330
Bos taurus LUZP1 VGNC VGNC:31084
Mus musculus LUZP1 MGD MGI:107629
Canis familiaris LUZP1 VGNC VGNC:42868
Macaca mulatta LUZP1 VGNC VGNC:100004
Rattus norvegicus LUZP1 RGD RGD:61839
Others LUZP1 NCBI