Pum2 - pumilio RNA-binding family member 2 Gene

Also Known as Pumm2; 5730503J23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 80913

Summary

Enables RNA binding activity. Acts upstream of or within posttranscriptional regulation of gene expression and stress granule assembly. Located in cytoplasmic stress granule. Is expressed in several structures, including adipose tissue; alimentary system; immune system; nervous system; and reproductive system. Orthologous to human PUM2 (pumilio RNA binding family member 2). [provided by Alliance of Genome Resources, Apr 2022]

Pum2 Products (6)

mRNA Protein Name
NM_001160219.1 NP_001153691.1 pumilio homolog 2 isoform 1
NM_001160220.1 NP_001153692.1 pumilio homolog 2 isoform 2
NM_001160221.1 NP_001153693.1 pumilio homolog 2 isoform 2
NM_001160222.1 NP_001153694.1 pumilio homolog 2 isoform 3
NM_001310519.1 NP_001297448.1 pumilio homolog 2 isoform 4
NM_030723.2 NP_109648.2 pumilio homolog 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
11780640 MGI
enables lncRNA binding IDA
IDA: Inferred from direct assay
30735131 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
18089289 MGI
enables pumilio-response element binding IDA
IDA: Inferred from direct assay
30735131 MGI
Biological Process GO Annotation Evidence References Source
involved in adipose tissue development IDA
IDA: Inferred from direct assay
30735131 MGI
involved in chromosome organization IDA
IDA: Inferred from direct assay
30735131 MGI
involved in hair follicle development IDA
IDA: Inferred from direct assay
30735131 MGI
involved in mitochondrion organization IDA
IDA: Inferred from direct assay
30735131 MGI
acts upstream of or within post-transcriptional regulation of gene expression IMP
IMP: Inferred from mutant phenotype
25100735 MGI
involved in respiratory electron transport chain IDA
IDA: Inferred from direct assay
30735131 MGI
involved in skeletal system development IDA
IDA: Inferred from direct assay
30735131 MGI
acts upstream of or within stress granule assembly IDA
IDA: Inferred from direct assay
16775137 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic stress granule IDA
IDA: Inferred from direct assay
16775137 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pumilio homolog 2

  • pumilio 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11462 PUM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22291 Pum2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28814 Pum2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pum2 NCBI NCBI:23369