2. Gene
  3. LBH - LBH regulator of WNT signaling pathway Gene

LBH - LBH regulator of WNT signaling pathway Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 81606 | Gene type: protein coding

About LBH

Cytogenetic location: 2p23.1 Genomic coordinates (GRCh38): 2:30,231,534-30,260,028 (from NCBI)

This gene has 9 transcripts (splice variants), 190 orthologues and 1 paralogue. Broad expression in lung (RPKM 81.1), lymph node (RPKM 54.3) and 23 other tissues.

Summary

Involved in negative regulation of transcription, DNA-templated; positive regulation of transcription, DNA-templated; and regulation of MAPK cascade. Located in cytoplasm and nucleus. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

LBH Products(1)

mRNA Protein Name
NM_030915.4 NP_112177.2 protein LBH

LBH Protein Structure

Lbh

Lbh: Cardiac transcription factor regulator, Developmental protein (18 - 105)

  • 0
  • 105 a.a.
Protein Preferred Names Protein Names

protein LBH

hLBH

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10224 Panobinostat 99.48% Yes
HY-10224A Panobinostat lactate / Unkown
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10224S Panobinostat-d4 / Unkown
HY-10224S1 Panobinostat-d4 hydrochloride / Unkown
HY-RS07542 LBH Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus LBH VGNC VGNC:81110
Bos taurus LBH VGNC VGNC:102824
Rattus norvegicus LBH RGD RGD:1584525
Mus musculus LBH MGD MGI:1925139