Apba2 - amyloid beta precursor protein binding family A member 2 Gene

Also Known as Mint2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 83610

Summary

Enables amyloid-beta binding activity. Predicted to be involved in chemical synaptic transmission and regulation of synaptic vesicle exocytosis. Predicted to act upstream of or within in utero embryonic development; locomotory behavior; and regulation of gene expression. Located in plasma membrane. Orthologous to human APBA2 (amyloid beta precursor protein binding family A member 2). [provided by Alliance of Genome Resources, Apr 2022]

Apba2 Products (1)

mRNA Protein Name
NM_031780.2 NP_113968.1 amyloid-beta A4 precursor protein-binding family A member 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables amyloid-beta binding IPI
IPI: Inferred from physical interaction
12196555 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9395480 RGD
Cellular Component GO Annotation Evidence References Source
is active in presynapse IDA
IDA: Inferred from direct assay
20369384 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

amyloid-beta A4 precursor protein-binding family A member 2

  • adapter protein X11beta

  • amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)

  • neuron-specific X11L protein

  • neuronal Munc18-1-interacting protein 2

Apba2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Apba2 O35431 Stxbp1 Rattus norvegicus P61765
Anti Bait CoIP
9395480
Intra
Apba2 O35431 Stxbp1 Rattus norvegicus P61765
Pull Down
9395480
Intra
Apba2 O35431 Tamalin Rattus norvegicus Q8R4T5
Anti Bait CoIP
12586822
Intra
Apba2 O35431 Tamalin Rattus norvegicus Q8R4T5
Pull Down
12586822
Cross
Apba2 O35431 APP Homo sapiens P05067
X-Ray Diffraction
22730553
Cross
Apba2 O35431 APP Homo sapiens P05067
Filter Binding
22730553
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00803 APBA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22391 Apba2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28915 Apba2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Apba2 NCBI NCBI:321