CD99L2 - CD99 molecule like 2 Gene

Also Known as CD99B; MIC2L1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 83692

About CD99L2

Cytogenetic location: Xq28 Genomic coordinates (GRCh38): X:150,766,336-150,898,668 (from NCBI)

This gene has 9 transcripts (splice variants), 181 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 33.3), fat (RPKM 18.8) and 23 other tissues.

Summary

This gene encodes a cell-surface protein that is similar to CD99. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

CD99L2 Products (5)

mRNA Protein Name
NM_001184808.2 NP_001171737.1 CD99 antigen-like protein 2 isoform 4 precursor
NM_001242614.2 NP_001229543.1 CD99 antigen-like protein 2 isoform 5 precursor
NM_031462.4 NP_113650.2 CD99 antigen-like protein 2 isoform 1 precursor
NM_134445.4 NP_604394.1 CD99 antigen-like protein 2 isoform 3 precursor
NM_134446.4 NP_604395.1 CD99 antigen-like protein 2 isoform 2 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CD99L2 Protein Structure

CD99L2

CD99L2: CD99 antigen like protein 2 (97 - 239)

  • 0
  • 100
  • 200
  • 262 a.a.
Protein Preferred Names Protein Names

CD99 antigen-like protein 2

  • MIC2 like 1

CD99L2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CD99L2 Q8TCZ2 UBQLN1 Homo sapiens Q9UMX0-2
Y2H Prey Pooling
26871637
Intra
CD99L2 Q8TCZ2 UBQLN1 Homo sapiens Q9UMX0-2
Validated Y2H
26871637
Intra
CD99L2 Q8TCZ2 UBQLN1 Homo sapiens Q9UMX0-2
Y2H Prey Pooling
25416956
Intra
CD99L2 Q8TCZ2 UBQLN1 Homo sapiens Q9UMX0-2
Y2H Array
26871637
Intra
CD99L2 Q8TCZ2 UBQLN1 Homo sapiens Q9UMX0-2
Validated Y2H
25416956
Intra
CD99L2 Q8TCZ2 UBQLN1 Homo sapiens Q9UMX0-2
Y2H Array
25416956
Intra
CD99L2 Q8TCZ2 SGTA Homo sapiens O43765
Validated Y2H
26871637
Intra
CD99L2 Q8TCZ2 SGTA Homo sapiens O43765
Y2H Array
26871637
Intra
CD99L2 Q8TCZ2 SGTA Homo sapiens O43765
Y2H Array
32296183
Intra
CD99L2 Q8TCZ2 SGTA Homo sapiens O43765
Y2H Prey Pooling
26871637
Intra
CD99L2 Q8TCZ2 SGTA Homo sapiens O43765
Y2H Prey Pooling
32296183
Intra
CD99L2 Q8TCZ2 UBQLN1 Homo sapiens Q9UMX0
Y2H Prey Pooling
26871637
Intra
CD99L2 Q8TCZ2 UBQLN1 Homo sapiens Q9UMX0
Validated Y2H
26871637
Intra
CD99L2 Q8TCZ2 UBQLN1 Homo sapiens Q9UMX0
Y2H Array
26871637
Intra
CD99L2 Q8TCZ2 SGTB Homo sapiens Q96EQ0
Y2H Array
32296183
Intra
CD99L2 Q8TCZ2 SGTB Homo sapiens Q96EQ0
Y2H Prey Pooling
32296183
Intra
CD99L2 Q8TCZ2 SGTB Homo sapiens Q96EQ0
Validated Y2H
32296183
Intra
CD99L2 Q8TCZ2 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
Intra
CD99L2 Q8TCZ2 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
Intra
CD99L2 Q8TCZ2 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CD99L2 Proteins

Cat. No. Product Name Accession Purity
HY-P72697 CD99L2 Protein, Human (HEK293, His) Q8TCZ2-1 (D26-A188) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Developmental And Epileptic Encephalopathy 65

  • DEE65

  • Epileptic Encephalopathy, Early Infantile, 65

  • Eiee65

  • Developmental And Epileptic Encephalopathy, 65

  • Early Infantile Epileptic Encephalopathy 65

  • Encephalopathy, Epileptic, Early Infantile, Type 65
Chronic Cervicitis
Cerebral Palsy

  • Infantile Cerebral Palsy

  • Mixed Cerebral Palsy

  • Palsy Cerebral

  • Palsy, Cerebral

  • Cerebral Palsy, Mixed
West Syndrome

  • Infantile Spasms

  • Infantile Spasms Syndrome

  • Infantile Spasm

  • X-Linked Infantile Spasm Syndrome

  • X-Linked Infantile Spasms

  • Epileptic Encephalopathy, Early Infantile, 1

  • Is

  • Tonic Spasms With Clustering, Arrest Of Psychomotor Development And Hypsarrhythmia On Eeg

  • West'S Syndrome

  • Spasms, Infantile

  • Is -[Infantile Spasm]

  • Salaam Spasm

  • Salaam Tic
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02281 CD99L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21834 Cd99l2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CD99L2 VGNC VGNC:70823
Felis catus CD99L2 VGNC VGNC:60644
Bos taurus CD99L2 VGNC VGNC:106678
Rattus norvegicus CD99L2 RGD RGD:620896
Mus musculus CD99L2 MGD MGI:2177151
Canis familiaris CD99L2 VGNC VGNC:54128
Others CD99L2 NCBI