ESYT3 - extended synaptotagmin 3 Gene

Also Known as E-Syt3; FAM62C; CHR3SYT

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 83850

Summary

Predicted to enable calcium ion binding activity; phosphatidylinositol binding activity; and phospholipid binding activity. Predicted to be involved in endoplasmic reticulum-plasma membrane tethering and lipid transport. Located in cytoplasmic side of plasma membrane; endoplasmic reticulum membrane; and endoplasmic reticulum-plasma membrane contact site. [provided by Alliance of Genome Resources, Jun 2026]
Biased expression in lung (RPKM 3.7), thyroid (RPKM 3.1) and 8 other tissues.

ESYT3 Products (3)

mRNA Protein Name
NM_001322831.2 NP_001309760.1 extended synaptotagmin-3 isoform a
NM_001322834.2 NP_001309763.1 extended synaptotagmin-3 isoform b
NM_031913.5 NP_114119.2 extended synaptotagmin-3 isoform a

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23791178 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic side of plasma membrane IDA
IDA: Inferred from direct assay
23791178 GOA
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
23791178 GOA
located in endoplasmic reticulum-plasma membrane contact site IDA
IDA: Inferred from direct assay
30220461 GOA
located in organelle membrane contact site IDA
IDA: Inferred from direct assay
23791178 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
17360437 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ESYT3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ESYT3 A0FGR9 ESYT2 Homo sapiens A0FGR8
Confocal
23791178
Intra
ESYT3 A0FGR9 ESYT2 Homo sapiens A0FGR8
Anti Tag CoIP
23791178
Intra
ESYT3 A0FGR9 ESYT2 Homo sapiens A0FGR8
Anti Tag CoIP
27065097
Intra
ESYT3 A0FGR9 ESYT1 Homo sapiens Q9BSJ8
Anti Tag CoIP
23791178
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04548 ESYT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04549 ESYT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14115 SYT3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22493 Esyt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22494 Esyt2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29016 Esyt1 Rat Pre-designed siRNA Set A / Unkown
HY-RS29017 Esyt2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown