TBC1D10A - TBC1 domain family member 10A Gene

Also Known as EPI64; TBC1D10; dJ130H16.1; dJ130H16.2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 83874

Summary

Enables GTPase activator activity and PDZ domain binding activity. Involved in positive regulation of proteolysis and retrograde transport, endosome to Golgi. Located in plasma membrane. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in esophagus (RPKM 13.6), placenta (RPKM 13.3) and 25 other tissues.

TBC1D10A Products (2)

mRNA Protein Name
NM_001204240.2 NP_001191169.1 TBC1 domain family member 10A isoform 1
NM_031937.3 NP_114143.1 TBC1 domain family member 10A isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables PDZ domain binding IPI
IPI: Inferred from physical interaction
11285285 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
11285285 GOA
Biological Process GO Annotation Evidence Références Source
involved in activation of cysteine-type endopeptidase activity IDA
IDA: Inferred from direct assay
18387192 GOA
involved in positive regulation of proteolysis IDA
IDA: Inferred from direct assay
18387192 GOA
NOT involved in regulation of cilium assembly IMP
IMP: Inferred from mutant phenotype
17646400 GOA
involved in retrograde transport, endosome to Golgi IMP
IMP: Inferred from mutant phenotype
17562788 GOA
Cellular Component GO Annotation Evidence Références Source
located in plasma membrane IDA
IDA: Inferred from direct assay
17562788 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TBC1D10A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
TBC1D10A Q9BXI6 TEX13A Homo sapiens Q9BXU3
Validated Y2H
25416956
Intra
TBC1D10A Q9BXI6 TEX13A Homo sapiens Q9BXU3
Y2H Prey Pooling
32296183
Intra
TBC1D10A Q9BXI6 TEX13A Homo sapiens Q9BXU3
Validated Y2H
32296183
Intra
TBC1D10A Q9BXI6 TEX13A Homo sapiens Q9BXU3
Y2H Array
32296183
Intra
TBC1D10A Q9BXI6 NHERF1 Homo sapiens O14745
Filter Binding
11285285
Intra
TBC1D10A Q9BXI6 ACD Homo sapiens Q96AP0
BiFC
21044950
Intra
TBC1D10A Q9BXI6 ACD Homo sapiens Q96AP0
Pull Down
21044950
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS14231 TBC1D10B Human Pre-designed siRNA Set A Pre-designed Set / Unkown