2. Gene
  3. CAMKK1 - calcium/calmodulin dependent protein kinase kinase 1 Gene

CAMKK1 - calcium/calmodulin dependent protein kinase kinase 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CAMKKA

Gene ID: 84254 | Gene type: protein coding

About CAMKK1

Cytogenetic location: 17p13.2 Genomic coordinates (GRCh38): 17:3,860,315-3,893,053 (from NCBI)

This gene has 4 transcripts (splice variants), 268 orthologues and 22 paralogues. Broad expression in brain (RPKM 12.8), salivary gland (RPKM 4.6) and 24 other tissues.

Summary

The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade. Three transcript variants encoding two distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

CAMKK1 Products(3)

mRNA Protein Name
NM_032294.3 NP_115670.1 calcium/calmodulin-dependent protein kinase kinase 1 isoform a
NM_172206.2 NP_757343.2 calcium/calmodulin-dependent protein kinase kinase 1 isoform c
NM_172207.3 NP_757344.2 calcium/calmodulin-dependent protein kinase kinase 1 isoform b

CAMKK1 Protein Structure

Pkinase

Pkinase: Protein kinase domain (128 - 409)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 505 a.a.
Protein Preferred Names Protein Names

calcium/calmodulin-dependent protein kinase kinase 1

CAMKK alpha protein

Related Diseases

Diseases Alias
Tracheitis

Acute Tracheitis

Chronic Tracheitis

Bacterial Tracheitis

Acute Tracheitis Nos

Tracheitis Nos

Tracheal Inflammation
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148063 DB0614 98.80% Unkown
HY-RS01865 CAMKK1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CAMKK1 VGNC VGNC:60336
Bos taurus CAMKK1 VGNC VGNC:26725
Rattus norvegicus CAMKK1 RGD RGD:62023
Mus musculus CAMKK1 MGD MGI:1891766
Canis familiaris CAMKK1 VGNC VGNC:38683
Macaca mulatta CAMKK1 VGNC VGNC:99125
Others CAMKK1 NCBI