FBXW9 - F-box and WD repeat domain containing 9 Gene

Also Known as Fbw9; MEC-15

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84261

Summary

Members of the F-box protein family, such as FBXW9, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Broad expression in testis (RPKM 5.8), kidney (RPKM 2.6) and 25 other tissues.

FBXW9 Products (1)

mRNA Protein Name
NM_032301.3 NP_115677.2 F-box/WD repeat-containing protein 9

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19159283 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FBXW9 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
FBXW9 Q5XUX1 SKP1 Homo sapiens P63208
MAPPIT
19159283
Intra
FBXW9 Q5XUX1 SKP1 Homo sapiens P63208
Anti Tag CoIP
19159283
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04818 FBXW7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04816 FBXW11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04815 FBXO9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04817 FBXW5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04819 FBXW8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16420 FBXW2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17548 Fbxw7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21128 Fbxw11 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21572 Fbxw2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24007 Fbxw7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27646 Fbxw11 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28090 Fbxw2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown