ALKBH7 - alkB homolog 7 Gene

Homo sapiens

Also known as ABH7; SPATA11; UNQ6002

Gene ID: 84266 | Gene type: protein coding

About ALKBH7

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:6,372,794-6,375,250 (from NCBI)

This gene has 3 transcripts (splice variants) and 192 orthologues. Broad expression in testis (RPKM 38.0), kidney (RPKM 14.9) and 24 other tissues.

Summary

Predicted to enable dioxygenase activity and metal ion binding activity. Involved in cellular response to DNA damage stimulus and regulation of mitochondrial membrane permeability involved in programmed necrotic cell death. Located in mitochondrial matrix. [provided by Alliance of Genome Resources, Apr 2022]

ALKBH7 Products(1)

mRNA	Protein	Name
NM_032306.4	NP_115682.1	alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial precursor

ALKBH7 Protein Structure

2OG-FeII_Oxy_2

0
100
200
221 a.a.

Protein Preferred Names

Protein Names

alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial

alkB, alkylation repair homolog 7

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00608	ALKBH7 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	ALKBH7	VGNC	VGNC:69663
Canis familiaris	ALKBH7	VGNC	VGNC:37807
Bos taurus	ALKBH7	VGNC	VGNC:25838
Felis catus	ALKBH7	VGNC	VGNC:59753
Rattus norvegicus	ALKBH7	RGD	RGD:1598126
Mus musculus	ALKBH7	MGD	MGI:1913650

Name
Email *

	Sorry, but the email address you supplied was invalid.