FNDC1 - fibronectin type III domain containing 1 Gene

Also Known as AGS8; FNDC2; MEL4B3; bA243O10.1; dJ322A24.1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84624

About FNDC1

Cytogenetic location: 6q25.3 Genomic coordinates (GRCh38): 6:159,169,400-159,272,108 (from NCBI)

This gene has 3 transcripts (splice variants), 200 orthologues and 1 paralogue. Biased expression in gall bladder (RPKM 10.5), thyroid (RPKM 9.5) and 12 other tissues.

Summary

Predicted to act upstream of or within several processes, including cellular response to hypoxia; positive regulation of cardiac muscle cell apoptotic process; and positive regulation of protein phosphorylation. Located in nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

FNDC1 Products (1)

mRNA Protein Name
NM_032532.3 NP_115921.2 fibronectin type III domain-containing protein 1 precursor

FNDC1 Protein Structure

fn3

fn3: Fibronectin type III domain (43 - 121)

fn3

fn3: Fibronectin type III domain (262 - 347)

fn3

fn3: Fibronectin type III domain (362 - 447)

fn3

fn3: Fibronectin type III domain (1658 - 1742)

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  • 1894 a.a.
Protein Preferred Names Protein Names

fibronectin type III domain-containing protein 1

  • activation-associated cDNA protein

Recombinant FNDC1 Proteins

Cat. No. Product Name Accession Purity
HY-P700995 FNDC1 Protein, Human (His) Q4ZHG4-1 (A33-T457) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Prostate Leiomyosarcoma

  • Leiomyosarcoma Of The Prostate
Prostate Sarcoma

  • Sarcoma Of The Prostate
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05018 FNDC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22511 Fndc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29032 Fndc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta FNDC1 VGNC VGNC:72546
Bos taurus FNDC1 VGNC VGNC:58376
Mus musculus FNDC1 MGD MGI:1915905
Rattus norvegicus FNDC1 RGD RGD:1310640
Felis catus FNDC1 VGNC VGNC:82362
Canis familiaris FNDC1 VGNC VGNC:40927
Others FNDC1 NCBI