SLX9 - SLX9 ribosome biogenesis factor Gene

Also Known as PRED56; FAM207A; C21orf70

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 85395

About SLX9

This gene has 5 transcripts (splice variants) and 194 orthologues. Ubiquitous expression in testis (RPKM 3.9), spleen (RPKM 3.7) and 25 other tissues.

Summary

Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of 90S preribosome and preribosome, small subunit precursor. [provided by Alliance of Genome Resources, Apr 2022]

SLX9 Products (7)

mRNA Protein Name
NM_001316983.2 NP_001303912.1 ribosome biogenesis protein SLX9 homolog isoform 2
NM_001316984.2 NP_001303913.1 ribosome biogenesis protein SLX9 homolog isoform 3
NM_001316985.2 NP_001303914.1 ribosome biogenesis protein SLX9 homolog isoform 4
NM_001316986.2 NP_001303915.1 ribosome biogenesis protein SLX9 homolog isoform 5
NM_001316987.2 NP_001303916.1 ribosome biogenesis protein SLX9 homolog isoform 6
NM_001316988.2 NP_001303917.1 ribosome biogenesis protein SLX9 homolog isoform 7
NM_058190.4 NP_478070.1 ribosome biogenesis protein SLX9 homolog isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLX9 Protein Structure

SLX9

SLX9: Ribosome biogenesis protein SLX9 (99 - 222)

  • 0
  • 100
  • 200
  • 230 a.a.
Protein Preferred Names Protein Names

ribosome biogenesis protein SLX9 homolog

  • family with sequence similarity 207 member A

SLX9 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SLX9 Q9NSI2 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra
SLX9 Q9NSI2 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra
SLX9 Q9NSI2 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
25416956
Intra
SLX9 Q9NSI2 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
SLX9 Q9NSI2 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Glutamate Formiminotransferase Deficiency

  • Formiminoglutamic Aciduria

  • Formiminotransferase Deficiency

  • FIGLU-URIA

  • Arakawa Syndrome 1

  • Formiminoglutamic Acidemia

  • Formiminotransferase Cyclodeaminase Deficiency

  • Formiminotransferase Deficiency Syndrome

  • Ftcd Deficiency

  • Formiminoglutamicaciduria

  • Figluria
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13391 SLX9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16010 ZDBF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SLX9 VGNC VGNC:28782
Felis catus SLX9 VGNC VGNC:102697
Canis familiaris SLX9 VGNC VGNC:40651
Rattus norvegicus SLX9 RGD RGD:1311257
Mus musculus SLX9 MGD MGI:1916334
Macaca mulatta SLX9 VGNC VGNC:72273
Others SLX9 NCBI