IDI2 - isopentenyl-diphosphate delta isomerase 2 Gene

Homo sapiens

Also known as IPPI2

Gene ID: 91734 | Gene type: protein coding

About IDI2

Cytogenetic location: 10p15.3 Genomic coordinates (GRCh38): 10:1,018,910-1,025,859 (from NCBI)

This gene has 1 transcript (splice variant), 149 orthologues and 1 paralogue. Ubiquitous expression in adrenal (RPKM 2.6), thyroid (RPKM 1.6) and 25 other tissues.

Summary

The protein encoded by this gene catalyzes the conversion of isopentenyl diphosphate to dimethylallyl diphosphate, which is a precursor for the synthesis of Cholesterol and other isoprenoids. This gene, which is a product of an ancestral gene duplication event, encodes a protein that may be involved in the aggregation of alpha-synuclein in the cerebral cortex of patients with Lewy body disease. In addition, segmental copy number gains in this locus have been associated with sporadic amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2016]

IDI2 Products(1)

mRNA	Protein	Name
NM_033261.3	NP_150286.1	isopentenyl-diphosphate delta-isomerase 2

IDI2 Protein Structure

NUDIX

0
100
200
227 a.a.

Protein Preferred Names

Protein Names

isopentenyl-diphosphate delta-isomerase 2

IPP isomerase 2

Recombinant IDI2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70903	IDI2 Protein, Human (His)	Q9BXS1 (M1-V227)	≥95%
HY-P70903A	IDI2 Protein, Human (C-His)	Q9BXS1 (D3-V227)	≥95%

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06537	IDI2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	IDI2	RGD	RGD:1559783
Mus musculus	IDI2	MGD	MGI:2444315
Others	IDI2	NCBI