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  2. GPR55 - G protein-coupled receptor 55 Gene

GPR55 - G protein-coupled receptor 55 Gene

Homo sapiens

Also known as LPIR1

Gene ID: 9290 | Gene type: protein coding

About GPR55

Cytogenetic location: 2q37.1 Genomic coordinates (GRCh38): 2:230,907,328-230,961,201 (from NCBI)

This gene has 6 transcripts (splice variants), 182 orthologues and 16 paralogues. Biased expression in testis (RPKM 2.7), spleen (RPKM 2.0) and 13 other tissues.

Summary

This gene belongs to the G-protein-coupled receptor superfamily. The encoded integral membrane protein is a likely Cannabinoid Receptor. It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways. [provided by RefSeq, Aug 2013]

GPR55 Products(4)

mRNA Protein Name
NM_005683.4 NP_005674.2 G-protein coupled receptor 55
XM_011512176.3 XP_011510478.1 G-protein coupled receptor 55 isoform X1
XM_005246952.5 XP_005247009.1 G-protein coupled receptor 55 isoform X1
XM_011512175.4 XP_011510477.1 G-protein coupled receptor 55 isoform X1

GPR55 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (38 - 288)

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  • 319 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 55

Related Diseases

Diseases Alias
Lennox-Gastaut Syndrome

Epileptic Encephalopathy Lennox-Gastaut Type

Lennox Syndrome

Encephalopathy Of Childhood

Childhood Epileptic Encephalopathy With Diffuse Slow Spikes And Waves

Lgs

Vulvar Syringoma
Cannabis Abuse

Marijuana Abuse

Cannabis Dependence

Marijuana Abuse

Cannabinoid Addiction

Cannabinoid Dependence

Cannabis Addiction

Childhood Electroclinical Syndrome
Hallucinogen Dependence

Hallucinogen Addiction

Dravet Syndrome

Severe Myoclonic Epilepsy Of Infancy

Smei

Severe Myoclonic Epilepsy In Infancy

Epileptic Encephalopathy, Early Infantile, 6

DRVT

Developmental And Epileptic Encephalopathy 6a

Dee6a

Eiee6

Dee6

Developmental And Epileptic Encephalopathy 6

Early Infantile Epileptic Encephalopathy 6

Myoclonic Epilepsy, Severe, Of Infancy

Sme

Severe Myoclonus Epilepsy Of Infancy

Borderline Smei

Smeb

Smeb-M

Smeb-O

Smeb-Sw

Smei-Borderland

Smei-Borderland More Than One Feature

Smei-Borderland-Myoclonic Seizures

Smei-Borderland-Spike Wave

Intractable Childhood Epilepsy With Generalized Tonic-Clonic Seizures

ICEGTC

Developmental And Epileptic Encephalopathy, 6

Infantile Severe Myoclonic Epilepsy

Epilepsy, Intractable Childhood, With Generalized Tonic-Clonic Seizures

Developmental And Epileptic Encephalopathy

Encephalopathy, Developmental And Epileptic

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Macaca mulatta GPR55 VGNC VGNC:104534
Canis familiaris GPR55 VGNC VGNC:41438
Mus musculus GPR55 MGD MGI:2685064
Bos taurus GPR55 VGNC VGNC:29591
Felis catus GPR55 VGNC VGNC:67433
Rattus norvegicus GPR55 RGD RGD:1559828