2. Gene
  3. HAUS8 - HAUS augmin like complex subunit 8 Gene

HAUS8 - HAUS augmin like complex subunit 8 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as DGT4; HICE1; NY-SAR-48

Gene ID: 93323 | Gene type: protein coding

About HAUS8

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:17,049,729-17,075,533 (from NCBI)

This gene has 8 transcripts (splice variants) and 165 orthologues. Broad expression in testis (RPKM 8.8), lymph node (RPKM 7.3) and 24 other tissues.

Summary

HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]

HAUS8 Products(2)

mRNA Protein Name
NM_001011699.1 NP_001011699.1 HAUS augmin-like complex subunit 8 isoform b
NM_033417.2 NP_219485.1 HAUS augmin-like complex subunit 8 isoform a
Protein Preferred Names Protein Names

HAUS augmin-like complex subunit 8

HEC1/NDC80 interacting, centrosome associated 1

Related Diseases

Diseases Alias
Phosphoglycerate Dehydrogenase Deficiency

Phgdh Deficiency

3-Phosphoglycerate Dehydrogenase Deficiency

PHGDHD

3-Pgdh Deficiency

3-Phosphoglycerate Dehydrogenase Deficiency, Infantile/Juvenile Form

Phgdh Deficiency, Infantile/Juvenile Form

Deficiency, Phosphoglycerate Dehydrogenase
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06020 HAUS8 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta HAUS8 VGNC VGNC:73259
Bos taurus HAUS8 VGNC VGNC:29763
Canis familiaris HAUS8 VGNC VGNC:41608
Felis catus HAUS8 VGNC VGNC:62760
Mus musculus HAUS8 MGD MGI:1923728
Rattus norvegicus HAUS8 RGD RGD:1311565