ECE2 - endothelin converting enzyme 2 Gene

Homo sapiens

Also known as EEF1AKMT4

Gene ID: 9718 | Gene type: protein coding

About ECE2

Cytogenetic location: 3q27.1 Genomic coordinates (GRCh38): 3:184,276,022-184,293,031 (from NCBI)

This gene has 9 transcripts (splice variants), 232 orthologues and 6 paralogues. Broad expression in adrenal (RPKM 4.6), brain (RPKM 3.0) and 22 other tissues.

Summary

Enables metalloendopeptidase activity. Involved in peptide hormone processing. Located in cytoplasmic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022]

ECE2 Products(3)

mRNA	Protein	Name
NM_001037324.3	NP_001032401.1	endothelin-converting enzyme 2 isoform B
NM_001100120.2	NP_001093590.1	endothelin-converting enzyme 2 isoform D
NM_001100121.2	NP_001093591.1	endothelin-converting enzyme 2 isoform E

Protein Preferred Names

Protein Names

endothelin-converting enzyme 2

EEF1A lysine methyltransferase 4

Recombinant ECE2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75266	ECE-2 Protein, Human (HEK293, His)	P0DPD8/NP_055508.3 (G199-W883)	≥95%
HY-P75267	ECE-2 Protein, Human (HEK293, hFc)	P0DPD8 (G199-W883)	≥95%

Related Diseases

Diseases

Alias

Periventricular Nodular Heterotopia

Periventricular Heterotopia	Pvnh
Familial Nodular Heterotopia	Heterotopia, Periventricular
Periventricular Heterotopia, X-Linked

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04134	ECE2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	ECE2	VGNC	VGNC:28303
Canis familiaris	ECE2	VGNC	VGNC:40182
Mus musculus	ECE2	MGD	MGI:1101356
Others	ECE2	NCBI