MAGEC1 - MAGE family member C1 Gene

Also Known as CT7; CT7.1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9947

About MAGEC1

Cytogenetic location: Xq27.2 Genomic coordinates (GRCh38): X:141,903,894-141,909,374 (from NCBI)

This gene has 2 transcripts (splice variants), 464 orthologues and 37 paralogues. Restricted expression toward testis (RPKM 5.4).

Summary

This gene is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, and therefore is about 800 aa longer than the Other MAGE proteins. [provided by RefSeq, Jul 2008]

MAGEC1 Products (1)

mRNA Protein Name
NM_005462.5 NP_005453.2 melanoma-associated antigen C1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17137291 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MAGEC1 Protein Structure

MAGE

MAGE: MAGE family (915 - 1084)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1142 a.a.
Protein Preferred Names Protein Names

melanoma-associated antigen C1

  • MAGE-C1 antigen

MAGEC1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
MAGEC1 O60732 CTAG1A Homo sapiens P78358
Y2H
17137291
Intra
MAGEC1 O60732 CTAG1A Homo sapiens P78358
Anti Bait CoIP
17137291
Intra
MAGEC1 O60732 CTAG1A Homo sapiens P78358
IF
17137291
Cross: Cross-species interaction Intra: Intraspecies interaction

MAGEC1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P85932 MAGE-C1 Antibody (YA5624) IHC-P, WB, ICC/IF, ELISA Human
HY-P85941 MAGE-C1 Antibody (YA5633) IHC-P, WB, ICC/IF, ELISA Human
HY-P86038 MAGE-C1 Antibody (YA5730) IHC-P, ELISA Human

Related Diseases

Diseases Alias
Melanoma

  • Malignant Melanoma

  • Cutaneous Melanoma

  • Naevocarcinoma

  • Malignant Melanomas
Malignant Anus Melanoma

  • Anal Melanoma

  • Malignant Melanoma Of Anus
Uterine Adnexa Cancer
Spermatocytoma

  • Spermatocytic Seminoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07973 MAGEC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MAGEC1 MGD MGI:1921687