MAGEC1 - MAGE family member C1 Gene

Homo sapiens

Also known as CT7; CT7.1

Gene ID: 9947 | Gene type: protein coding

About MAGEC1

Cytogenetic location: Xq27.2 Genomic coordinates (GRCh38): X:141,903,894-141,909,374 (from NCBI)

This gene has 2 transcripts (splice variants), 464 orthologues and 37 paralogues. Restricted expression toward testis (RPKM 5.4).

Summary

This gene is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, and therefore is about 800 aa longer than the other MAGE proteins. [provided by RefSeq, Jul 2008]

MAGEC1 Products(1)

mRNA	Protein	Name
NM_005462.5	NP_005453.2	melanoma-associated antigen C1

MAGEC1 Protein Structure

MAGE

0
200
400
600
800
1000
1142 a.a.

Protein Preferred Names

Protein Names

melanoma-associated antigen C1

MAGE-C1 antigen

Related Diseases

Diseases

Alias

Melanoma

Malignant Melanoma	Cutaneous Melanoma
Naevocarcinoma	Malignant Melanomas

Malignant Anus Melanoma

Anal Melanoma

Malignant Melanoma Of Anus

Uterine Adnexa Cancer

Spermatocytoma

Spermatocytic Seminoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07973	MAGEC1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	MAGEC1	MGD	MGI:1921687

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