1. GPCR/G Protein
  2. Glucocorticoid Receptor
  3. Glucocorticoid receptor agonist-1

Glucocorticoid receptor agonist-1 

Cat. No.: HY-131974
Handling Instructions

Glucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM extracted from patent WO2017210471A1, compound 41.

For research use only. We do not sell to patients.

Glucocorticoid receptor agonist-1 Chemical Structure

Glucocorticoid receptor agonist-1 Chemical Structure

CAS No. : 2166375-82-0

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5 mg USD 750 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1250 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Glucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM extracted from patent WO2017210471A1, compound 41[1].

IC50 & Target

IC50: 2.8 nM (Glucocorticoid receptor)[1]

In Vitro

Glucocorticoid receptor agonist immunoconjugates are useful for treating autoimmune diseases such as, but not limited to, rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, adult Crohn's disease, pediatric Crohn's disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, uveitis, Behcets disease, a spondyloarthropathy, or psoriasis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

569.69

Formula

C₃₅H₃₉NO₆

CAS No.

2166375-82-0

SMILES

OCC([[email protected]]12[[email protected]@]3([[email protected]@]([[email protected]@]4([H])[[email protected]]([[email protected]@]5(C(CC4)=CC(C=C5)=O)C)([H])[[email protected]](C3)O)([H])C[[email protected]@]1([H])O[[email protected]](C6=CC=C(C=C6)CC7=CC(N)=CC=C7)([H])O2)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

References
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Keywords:

Glucocorticoid receptor agonist-1Glucocorticoid receptor agonist1Glucocorticoid receptor agonist 1Glucocorticoid ReceptorImmunoconjugatesautoimmunerheumatoid arthritisInhibitorinhibitorinhibit

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Glucocorticoid receptor agonist-1
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HY-131974
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