GSK-3β inhibitor 11
Based on 1 Customer Validation
GSK-3β inhibitor 11 (compound 21) is a glycogen synthase kinase-3β (GSK-3β) inhibitor (IC50=10.02 μM). GSK-3β inhibitor 11 can be used in neurodegenerative disease research.
For research use only. We do not sell to patients.
- Purity: 98.02%
- CAS No.: 536731-65-4
- Formula: C20H15N3O4S
- Molecular Weight:393.42
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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GSK-3β 10.02 μM (IC50) |
Chemical Information
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CAS No. 536731-65-4
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Appearance Solid
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Molecular Weight 393.42
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Formula C20H15N3O4S
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Color White to light yellow
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SMILES
O=C1C2=C(C(N1CC(NC3=NC(C4=CC(OC)=CC=C4)=CS3)=O)=O)C=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 20.83 mg/mL (52.95 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5418 mL | 12.7091 mL | 25.4181 mL | 63.5453 mL |
| 5 mM | 0.5084 mL | 2.5418 mL | 5.0836 mL | 12.7091 mL | |
| 10 mM | 0.2542 mL | 1.2709 mL | 2.5418 mL | 6.3545 mL | |
| 15 mM | 0.1695 mL | 0.8473 mL | 1.6945 mL | 4.2364 mL | |
| 20 mM | 0.1271 mL | 0.6355 mL | 1.2709 mL | 3.1773 mL | |
| 25 mM | 0.1017 mL | 0.5084 mL | 1.0167 mL | 2.5418 mL | |
| 30 mM | 0.0847 mL | 0.4236 mL | 0.8473 mL | 2.1182 mL | |
| 40 mM | 0.0635 mL | 0.3177 mL | 0.6355 mL | 1.5886 mL | |
| 50 mM | 0.0508 mL | 0.2542 mL | 0.5084 mL | 1.2709 mL |
GSK-3β inhibitor 11 Related Classifications
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