hCAII/XII-IN-1
hCAII/XII-IN-1 (compound 4l) is a potent inhibitor of hCAXII and hCAII, with Kis of 8.4 and 9.4 nM, respectively. hCAXII-IN-11 plays an important role in cancer research.
For research use only. We do not sell to patients.
- Formula: C22H20N4O6S2
- Molecular Weight:500.55
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
hCA XII 8.4 nM (Ki) |
CA Ⅱ 9.4 nM (Ki) |
Chemical Information
-
Molecular Weight 500.55
-
Formula C22H20N4O6S2
-
SMILES
OC1=CC=CC=C1C(C=C(NC2=CC(S(=O)(N)=O)=CC=C2)C3=O)N3C4=CC(S(=O)(N)=O)=CC=C4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Cristina M Al-Matarneh, et al. Novel 3-Sulfonamide Dual-Tail Pyrrol-2-one Bridged Molecules as Potent Human Carbonic Anhydrase Isoform Inhibitors: Design, Synthesis, Molecular Modeling Investigation, and Anticancer Activity in MeWo, SK-BR-3, and MG-63 Cell Lines. J Med Chem. 2025 Jan 10. doi: 10.1021/acs.jmedchem.4c02586. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
hCAII/XII-IN-1 Related Classifications
HY-168856 Related Classifications
Powered by Bioz