Hydrocortisone phosphate sodium
Based on 1 Customer Validation
Hydrocortisone phosphate sodium is a soft steroid with low anti-inflammatory properties and a short duration of action. Hydrocortisone phosphate sodium can be used for the research for several ocular conditions and gastric ulcers.
For research use only. We do not sell to patients.
- Purity: 99.11%
- CAS No.: 6000-74-4
- Formula: C21H29Na2O8P
- Molecular Weight:486.40
-
Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Wistar rats[2]
-
Dosage:2.5 mg/kg
-
Administration:2.5 mg/kg, ip., daily
-
Result:Resulted in a significant delay of ulcer healing induced by acetic acid.
Chemical Information
-
CAS No. 6000-74-4
-
Appearance Solid
-
Molecular Weight 486.40
-
Formula C21H29Na2O8P
-
Color White to off-white
-
SMILES
C[C@@]12[C@](CC[C@]2(O)C(COP(O[Na])(O[Na])=O)=O)([H])[C@@]3([H])[C@]([C@@]4(C(CC3)=CC(CC4)=O)C)([H])[C@@H](O)C1
-
Synonyms
Hydrocortisone 21-phosphate sodium; Cortisol 21-phosphate sodium
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 70 mg/mL (143.91 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (274 KB)
-
SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
-
Handling Instructions (2659 KB)
References
[1]. Carlo Cagini, et al. Kinetics of hydrocortisone sodium phosphate penetration into the human aqueous humor after topical application. Int J Clin Pract. 2021 Dec;75(12):e14987. [Content Brief]
[2]. H Kuwayama, et al. Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. Am J Med. 1991 Aug 8;91(2A):15S-19S. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.0559 mL | 10.2796 mL | 20.5592 mL | 51.3980 mL |
| 5 mM | 0.4112 mL | 2.0559 mL | 4.1118 mL | 10.2796 mL | |
| 10 mM | 0.2056 mL | 1.0280 mL | 2.0559 mL | 5.1398 mL | |
| 15 mM | 0.1371 mL | 0.6853 mL | 1.3706 mL | 3.4265 mL | |
| 20 mM | 0.1028 mL | 0.5140 mL | 1.0280 mL | 2.5699 mL | |
| 25 mM | 0.0822 mL | 0.4112 mL | 0.8224 mL | 2.0559 mL | |
| 30 mM | 0.0685 mL | 0.3427 mL | 0.6853 mL | 1.7133 mL | |
| 40 mM | 0.0514 mL | 0.2570 mL | 0.5140 mL | 1.2850 mL | |
| 50 mM | 0.0411 mL | 0.2056 mL | 0.4112 mL | 1.0280 mL | |
| 60 mM | 0.0343 mL | 0.1713 mL | 0.3427 mL | 0.8566 mL | |
| 80 mM | 0.0257 mL | 0.1285 mL | 0.2570 mL | 0.6425 mL | |
| 100 mM | 0.0206 mL | 0.1028 mL | 0.2056 mL | 0.5140 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.