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Cat. No.: HY-B1155

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Hydrocortisone phosphate

(Synonyms: Hydrocortisone 21-phosphate; Cortisol 21-phosphate)

Hydrocortisone phosphate (Hydrocortisone 21-phosphate) is a derivative of the glucocorticoid Hydrocortisone hemisuccinate (HY-B1402) that increases serum luteinizing hormone (LH) levels. Hydrocortisone phosphate increases the activity of magnesium-dependent polymerases in the nucleolus. Hydrocortisone phosphate also serves as a substrate for alkaline phosphatase to localize phosphatases that hydrolyze steroid phosphates, and the role of alkaline phosphatase has been validated in adult mouse tissues.

For research use only. We do not sell to patients.

CAS No.: 3863-59-0
Formula: C₂₁H₃₁O₈P
Molecular Weight:442.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Hydrocortisone phosphate Chemical Structure

CAS No.: 3863-59-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 3863-59-0
Molecular Weight 442.44
Formula C₂₁H₃₁O₈P
SMILES

C[C@@]12[C@](C(COP(O)(O)=O)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O
Synonyms

Hydrocortisone 21-phosphate; Cortisol 21-phosphate
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Botte V, et al. "The hydrocortisone 21-phosphate as substrate for alkaline phosphatase: Histochemical remarks." Histochemie 16.2 (1968): 195-196. [Content Brief]

[2]. Jacob, et al. Munro. "Regulation of nucleolar RNA metabolism by hydrocortisone." European Journal of Biochemistry 7.4 (1969): 449-453. [Content Brief]

[3]. Kowalski, et al. "Effects of subchronic implantation of hydrocortisone phosphate-releasing osmotic pumps on peripheral gonadotropin levels and estradiol feedback to gonadotropin secretion in the cynomolgus monkey." Neuroendocrinology 57.2 (1993): 330-339. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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